Preliminary research of contrast enhanced ultrasound in evaluating the survival value of allotopic autotransplantation

doi:10.11958/20220388

Abstract

Abstract:

Objective To investigate the value of contrast enhanced ultrasound (CEUS) in determining graft survival after parathyroidectomy and autologous parathyroid ectopic transplantation. Methods Seventeen patients with renal failure complicated by secondary hyperparathyroidism underwent autotransplantation of parathyroid gland were collected. In each case, 4 parathyroid tissues (68 in total) were transplanted between subcutaneous and adipose tissue of the forearm without venostomy. CEUS was performed 15-21 days after transplantation to observe the enhancement of blood supply of the graft and to estimate whether the parathyroid gland survived and had secretory function after transplantation. According to whether all the grafts showed enhancement, the grafts were divided into the partial successful group and the all successful group. The survival of the grafts was determined by comparing the parathyroid hormone (PTH) levels of bilateral cephalic veins 30 days after surgery. Results Among the 17 patients, there were 8 patients in the all successful group and 9 patients in the partial successful group. PTH levels were higher in the cephalic vein of the transplanted side than those of the non-transplanted side. The levels of PTH in the cephalic vein were significantly higher in the all successful group than those in the partial successful group (P<0.05). Conclusion CEUS can assess the survival rate of parathyroidectomy and autotransplantation more accurately and specifically at an earlier stage.

Key words: ultrasonography,doppler,color, contrast media, parathyroid glands, hyperparathyroidism,secondary, transplantation,autologous, contrast enhanced ultrasound, rate of survival

CLC Number:

R445.1

Figures/Tables 2

References 19

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组别	n	移植侧	非移植侧	t
全部移植成功组	8	93.188±49.042	17.436±7.053	4.324^＊＊
部分移植成功组	9	31.163±7.798	9.778±3.413	7.537^＊＊
t		3.756^＊＊	2.794^＊

组别	n	移植侧	非移植侧	t
全部移植成功组	8	93.188±49.042	17.436±7.053	4.324^＊＊
部分移植成功组	9	31.163±7.798	9.778±3.413	7.537^＊＊
t		3.756^＊＊	2.794^＊