Emphasize the role of electrophysiological measurements in the diagnosis of amyotrophic lateral sclerosis

doi:10.11958/20230474

Abstract

Abstract:

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by loss of upper and lower motor neurons, resulting in progressive weakness and wasting of all voluntary muscles, culminating in respiratory failure. Neuroelectrophysiological detection plays an an essential role in early diagnosis of ALS, and can even detect subclinical dysfunction. Nerve conduction and needle electromyography, as standard neurophysiological detection method, are very important for early detection of lower motor neuron disease. Many emerging techniques for estimating the number of motor units have been proposed to increase diagnostic sensitivities and used to assess ALS progression.

Key words: amyotrophic lateral sclerosis, electrophysiological measurements, nerve conduction study, electromyography

CLC Number:

R746.4

References 19

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