Abstract:

Objective To compare the clinical effects of CT-guided and endoscopic surgical percutaneous gastrostomy in patients with amyotrophic lateral sclerosis (ALS). Methods The clinical data of 104 patients with ALS were retrospectively analyzed, including 48 patients underwent CT-guided percutaneous gastrostomy (CT-guided group) and 56 patients underwent endoscopic percutaneous gastrostomy (endoscopic group). The disease status, length of hospital stay, postoperative length of hospital stay, postoperative complications, and survival rates of six months and one year after surgery were compared between the two groups. Results There were no significant differences in age, disease course, dysphagia time, height, body weight and preoperative nutritional status between the two groups (P>0.05). The length of hospital stay and postoperative length of stay were shorter in the CT-guided group than those in the endoscopic group (P<0.05). There was no significant difference in the incidence of complications between the endoscopic group (19.6%) and the CT-guided group (8.3%, P>0.05). There was no significant difference in one-year survival rate between the endoscopic group and the CT-guided group (91.0% vs. 93.8%, Log-rank χ²=1.606, P>0.05). Conclusion CT-guided percutaneous gastrostomy shows its advantages in ALS, especially in shortening the length of hospital stay and postoperative length of hospital stay in ALS patients, and is worthy of widespread clinical application.

Key words: amyotrophic lateral sclerosis, percutaneous gastrostomy, dysphagia, complications, length of hospital stay