Abstract:

Objective To investigate the nutritional status of hyperemesis gravidarum (HG) patients and its influence on pregnancy outcome. Methods A total of 153 cases of HG and their newborns were taken as the observation group, and 350 cases of healthy women and their newborns were used as the control group. The characteristics of pregnant women and pregnancy outcomes were compared between the two groups. In patients with HG, 7 newborns were in the low birth weight group and 146 cases in the normal birth weight group. The levels of fast reaction protein, vitamin and trace element were analyzed in the two groups. Results Compared with the control group, the mean birth weight of newborns was lower, the preterm birth rate was higher, the proportion of low birth weight was higher and the probability of female birth was higher in the observation group (P<0.05). Micronutrient deficiency was common in the observation group, especially vitamin D, serum manganese and zinc deficiency. Compared with the normal body weight group, more weight loss and lower levels of zinc, iron and vitamin C during pregnancy in the low birth weight group (P<0.05). Conclusion HG patients should pay attention to the supplementation of vitamin D, manganese, and zinc. Low birth weight of newborns is associated with a higher level of decline in pregnancy body weight and lower levels of zinc, iron,and vitamin C during pregnancy.

Key words: hyperemesis gravidarum, malnutrition, pregnancy outcome, infant, premature, low birth weight