Distribution characteristics and risk factor analysis of metabolic syndrome in children in Lubei district of Tangshan City from 2020 to 2024

doi:10.11958/20241665

Abstract

Abstract:

Objective To investigate the clinical distribution and risk factors of metabolic syndrome (MS) in children from Lubei district of Tangshan City from 2020 to 2024. Methods A total of 964 children were identified by multi-segment stratified cluster sampling. A questionnaire survey was conducted on all subjects, and the recovery rate of the questionnaire was 98.0%, with 945 samples recovered. The detection rates of MS in different populations were compared, and risk factors of MS in children were analysed by Logistic regression analysis. Results In 945 children, 49 (5.19%) had MS, and there was no significant difference in detection rate between different genders of children (P > 0.05). There were no significant differences in blood pressure [systolic blood pressure (SBP) and diastolic blood pressure (DBP)], blood lipid [triglycerides (TG) and high density lipoprotein cholesterol (HDL-C)] between children ages 7 to 10 years old and 11 to 14 years old (P > 0.05). The values of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C) and waist circumference (WC) were higher in boys aged 11-14 than those in girls (P < 0.05). The proportion of body weight and obesity, the proportion of physical activity time < 10 h/ week, the proportion of family history of hypertension and WC level were higher in the MS group than those in the non-MS group (P < 0.05). Multivariate Logistic regression model showed that weight obesity, physical activity time < 10 h/week, family history of hypertension and high WC value were independent risk factors for MS in children (P < 0.05). Conclusion Obesity, family history of hypertension, time spent in physical activity and higher WC are strongly associated with the development of MS in children, and clinical attention should be paid to them.

Key words: metabolic syndrome, child, risk factors, Logistic models

CLC Number:

R174.6

Figures/Tables 4

References 24

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性别		7岁~					8岁~						9岁~					10岁~
性别		n			MS		n		MS				n		MS			n		MS
男		53			2（3.77）		75				3（4.00）		64				4（6.25）	81				7（8.64）
女		37			1（2.70）		43				1（2.33）		48				2（4.17）	60				4（6.67）
χ²		0.000					0.000						0.004					0.013
性别	11岁~					12岁~						13岁~							14岁
性别	n		MS			n		MS				n		MS					n		MS
男	96			6（6.25）		84				6（7.14）		52				1（1.92）			53				2（3.77）
女	73			3（4.11）		58				5（8.62）		31				1（3.23）			37				1（2.70）
χ²	0.072					0.000						1.000^▲							0.078

性别		7岁~					8岁~						9岁~					10岁~
性别		n			MS		n		MS				n		MS			n		MS
男		53			2（3.77）		75				3（4.00）		64				4（6.25）	81				7（8.64）
女		37			1（2.70）		43				1（2.33）		48				2（4.17）	60				4（6.67）
χ²		0.000					0.000						0.004					0.013
性别	11岁~					12岁~						13岁~							14岁
性别	n		MS			n		MS				n		MS					n		MS
男	96			6（6.25）		84				6（7.14）		52				1（1.92）			53				2（3.77）
女	73			3（4.11）		58				5（8.62）		31				1（3.23）			37				1（2.70）
χ²	0.072					0.000						1.000^▲							0.078

年龄组	性别	n	SBP/mmHg	DBP/mmHg	TG/（mmol/L）	TC/（mmol/L）	LDL-C/（mmol/L）	HDL-C/（mmol/L）	WC/cm
7~10岁	男	273	98.80±4.96	60.03±3.99	1.18±0.38	4.72±0.96	2.81±0.70	1.20±0.33	58.71±5.68
7~10岁	女	188	98.79±5.00	59.99±4.24	1.16±0.38	4.80±0.90	2.82±0.66	1.18±0.32	57.81±7.21
	t		0.013	0.080	0.630	0.860	0.200	0.555	1.493
11~14岁	男	285	99.51±5.01	60.39±4.09	1.21±0.42	4.86±0.85	2.90±0.55	1.18±0.33	59.56±7.10
11~14岁	女	199	99.74±5.08	60.03±4.15	1.21±0.43	4.12±0.69	2.75±0.64	1.17±0.28	58.10±6.55
	t		0.497	0.937	0.025	10.227^＊＊	2.573^*	0.524	2.306^＊

年龄组	性别	n	SBP/mmHg	DBP/mmHg	TG/（mmol/L）	TC/（mmol/L）	LDL-C/（mmol/L）	HDL-C/（mmol/L）	WC/cm
7~10岁	男	273	98.80±4.96	60.03±3.99	1.18±0.38	4.72±0.96	2.81±0.70	1.20±0.33	58.71±5.68
7~10岁	女	188	98.79±5.00	59.99±4.24	1.16±0.38	4.80±0.90	2.82±0.66	1.18±0.32	57.81±7.21
	t		0.013	0.080	0.630	0.860	0.200	0.555	1.493
11~14岁	男	285	99.51±5.01	60.39±4.09	1.21±0.42	4.86±0.85	2.90±0.55	1.18±0.33	59.56±7.10
11~14岁	女	199	99.74±5.08	60.03±4.15	1.21±0.43	4.12±0.69	2.75±0.64	1.17±0.28	58.10±6.55
	t		0.497	0.937	0.025	10.227^＊＊	2.573^*	0.524	2.306^＊

组别	n	性别			当前BMI				开始睡觉时间				体力活动水平			体育活动时间
组别	n	男		女	正常		超重	肥胖	22点前		22点后		中等强度	高强度		<10 h/周	≥10 h/周
非MS组	896	527（58.8）		369（41.2）	273（30.5）		428（47.8）	195（21.8）	602（67.2）		294（32.8）		359（40.1）	537（59.9）		380（42.4）	516（57.6）
MS组	49	31（63.3）		18（36.7）	11（22.5）		16（32.7）	22（44.9）	30（61.2）		19（38.8）		23（46.9）	26（53.1）		35（71.4）	14（28.6）
χ²		0.380			14.082^＊＊				0.746				0.911			40.328^＊＊
组别		电子屏幕暴露时间			家族史						WC/cm	BMI/（kg/m²）			SBP/mmHg		DBP/mmHg
组别		<2 h/d		≥2 h/d	肥胖		高血压		糖尿病		WC/cm	BMI/（kg/m²）			SBP/mmHg		DBP/mmHg
非MS组		156（17.4）		740（82.6）	523（58.8）		498（55.6）		676（75.5）		58.08±6.27	17.71±2.19			99.24±5.00		60.07±4.11
MS组		11（22.5）		38（77.6）	31（63.3）		36（73.8）		34（69.4）		69.29±3.86	18.33±3.28			98.63±5.30		61.12±3.73
χ²或t		0.811			0.459		6.050^＊		0.913		12.385^＊＊	1.897			0.829		1.743
组别			FPG/（mmol/L）			TG/（mmol/L）				TC/（mmol/L）			LDL-C/（mmol/L）			HDL-C/（mmol/L）
非MS组			4.65±0.42			1.19±0.41				4.65±0.90			2.82±0.64			1.19±0.314
MS组			4.73±0.37			1.27±0.36				4.72±0.93			2.99±0.63			1.14±0.356
t			1.482			1.355				0.512			1.882			0.915