Abstract: 【Abstract】 Objective To observe the change and correlation of abdominal space in different CO2 pneumoperitoneum pressure. Methods Twenty cases undergoing laparoscopic surgery were monitored cubic abdominal circumference, HR, MAP, SiO2, PETCO2 before pneumoperitoneum, pneumoperitoneum pressure 5mmHg and 10mmHg. Result Cubic abdominal circumference, HR, MAP, PETCO2 significantly increased with pneumoperitoneum pressure increasing, P<0.05. Abdominal cavity volume would be increased 35% by pneumoperitoneum pressure 5mmHg, while get another 11% abdominal cavity volume by 10mmHg. Conclusion Since lower pneumoperitoneum pressure could meet requirement of laparoscopic operation, we should pay more attention to the interference of CO2 pneumoperitoneum on physiological function.

Key words: laparoscopic surgery, pneumoperitoneum, pressure, neonates, younger infants