Abstract: Abstract: 【Objective】 To investigate clinical curative effect on endoscopic sphincterotomy ( EST ) combined with laparoscopic cholecystectomy ( LC ) and laparotomy in treatment of cholecystolithiasis and choledocholithiasis.【Method】60 cases with cholecystolithiasis and choledocholithiasis collected were analyzed,compared the effect of double mirror minimally invasive operation ( 30 cases) and laparotomy (30 cases ).【Results】Double mirror minimally invasive operation was significantly better than laparotomy in bleeding,hospitalization time, residual stone rate and infection of incisional wound ( P < 0.05 ), The difference was statistically significant in iatrogenic pancreatitis rate(23.3%)and bile leakage rate(13.3%) .【Conclusion】There are less trauma, less bleeding, shorter hospitalization time, no residual stones, rapid postoperative recovery in double mirror minimally invasive treatment of gallstones and bile duct stones, still some complications.

Key words: ERCP, EST, laparoscopic cholecystectomy, cholecystolithiasis, choledocholithiasis