Abstract: Abstract   Objectives   To study the relationship between red cell distribution width（RDW）,direct-bilirubin（D-BIL）and paroxysmal atrial fibrillation(AF) in patients with hypertension. Method     Eighty patients, who were hospitalized in Second Hospital of Tianjin Medical University from October 2011 to April 2012,were enrolled in this study. The patients were divided into two groups: AF group and control group, according to the history of AF. The baseline clinical data were collected including age, sex, combined cardiovascular diseases, laboratory results and findings from echocardiography. The RDW and D-BIL level were compared and logistic regression model was established to identify the potential risk factors for paroxysmal AF. Results    The levels of RDW and D-BIL were significantly higher（P<0.05）in patients with AF than those in control group. Logistic regression analysis showed D-BIL and left atrial diameter（LAD）were the independent risk factors for the development of paroxysmal AF. Conclusion     The higher level of D-BIL may relate to the development of paroxysmal AF in hypertensive patients.

Key words: atrial fibrillation, Serum bilirubin, hypertension