Abstract: [Abstract]  Objective  To investigate the relationship of T peak-T end (Tp-Te) interval and Tp-Te interval dispersion (Tp-Ted) in different periods of myocardial ischemia in patients with acute myocardial infarction (AMI), and to assess the clinical significance of Tp-Te and Tp-Ted for prediction of the ventricular arrhythmia (VA). Methods   A total of 80 patients with AMI were enrolled in the study. The sizes and changes of Tp-Te and Tp-Ted were observed during the acute phase and recovery phase in patients. The differences of Tp-Te and Tp-Ted were compared between ventricular tachycardia group (A group), ventricular premature beats group (B group) and non- ventricular arrhythmia group (C group). Results   The values of Tp-Te and Tp-Ted were obviously longer in acute period [(125.22±17.70) ms and (54.76±13.26) ms] than those in recovery period[ (113.84±17.37) ms and (42.06±13.95)ms] (P＜ 0.01). The values of Tp-Te and Tp-Ted were significantly longer in A group[ (134.82±19.56) ms and (62.00±15.19) ms] than those in B [(122.94±15.09) ms and (54.09±10.56)ms ]and C group [(110.09±15.21) ms and (45.27±9.85) ms]. The values were higher in B group than those of C group. Conclusion   The Tp-Te interval and Tp-Ted prolongated in acute phase than those of recovery phase in patients with AMI. TpTe interval and Tp-Ted can be used as an important index to predict VA in patients with AMI.

Key words: acute myocardiac infarction, acute disease, arrhythmias, cardiac, action potential, Electrocardiography, Tpeak-Tend interval, T波峰-末间期离散度