Abstract: Objective To evaluate the safety and efficacy of treating bifurcation lessions with jailed-balloon technique in simple strategy. Methods Ninety patients with bifurcation lessions (Duke D or F type) who received the side branch protection technique with simple strategy were involved in a single center retrospective analysis. Patients were randomly divided into jailedballoon protection group (n=48) and jailed guidewire group (n=42). The process operating, procedural success of percutaneous coronary intervention (PCI) and percutaneous transluminal coronary angioplasty (PTCA), complications and the results of followup were investigated. Results The clinical baseline date and the bifurcation lesions were not significant different between jailedballoon group and jailed guidewire group (P > 0.05). The procedural success rate of PCI was 100% in jailed-balloon group and 97.6% in jailed guidewire group, no significance difference user between two groups (P > 0.05). The perioperative complications (the rate of no reflow) was lower in jailed-balloon group than those of jailed guidewire group (1.0% vs. 19.0%, P < 0.05). The procedural success rate of PTCA were lower in jailed-balloon group than that of jailed guidewire group (4.2% vs. 23.8%, P < 0.01). The total operation time [(56.40±11.71) s vs. (72.60±10.62) s]， exposing time [(9.86±1.82) s vs.(12.24±2.32)s] or amount of used contrast agent [(90.54±15.26) mL vs. (118.16±18.64) mL] were significantly lower in jailed-balloon group compared with those of jailed guidewire group (P＜ 0.05). At the 12-month follow-up, the MACE was lower in the jailed-balloon group than that of jailed guidewire group (16.7% vs. 38.1%, P < 0.05). The restenotic rate (2.1% vs. 4.8%, P > 0.05) and the maximum restenotic level (19.24% vs. 21.46%， P > 0.05) in the main branch were not significant different between jailed-balloon group and jailed guidewire group. But the maximum restenotic level in the opening of side branch was lower in jailed-balloon group than that of jailed guidewire group (51.2% vs. 72.46%, P < 0.01). Conclusion The jailed-balloon technique reduces the operation complications, exposure time and amount of contrast agent, and also saves surgical consumables. The procedure of branch with simple strategy is safe and effective in treatment of bifurcation lesions.

Key words: coronary disease, myocardial infarction, angioplasty, transluminal, percutaneous coronary, myocardial reperfusion, myocardial reperfusion injury, jailed balloon technique