天津医药

天津医药 ›› 2019, Vol. 47 ›› Issue (6): 663-666.doi: 10.11958/20181446

• 综述 • 上一篇    下一篇

饱和脂肪酸与心血管疾病关系的研究进展

车娟， 刘姣， 朱玉芳， 陈海英△   

  1. 石家庄， 河北医科大学 （邮编050011）
  • 收稿日期:2018-09-25 修回日期:2019-03-02 出版日期:2019-06-15 发布日期:2019-06-15
  • 通讯作者: 车娟 E-mail:cj932016@163.com
  • 基金资助:
    河北省科技计划项目;河北省中医药管理局计划项目

Advances in the relationship between saturated fatty acids and cardiovascular diseases

CHE Juan, LIU Jiao, ZHU Yu-fang, CHEN Hai-ying△   

  1. Hebei Medical University, Shijiazhuang 050011, China
  • Received:2018-09-25 Revised:2019-03-02 Published:2019-06-15 Online:2019-06-15
  • Contact: Juan CHE E-mail:cj932016@163.com

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摘要： 摘要： 关于饱和脂肪酸 （SFA） 对心血管疾病的作用现在观点不一， 食物种类来源、 SFA碳链的奇偶和链长是很大的影响因素。本文回顾了饱和脂肪酸对心血管疾病危险因素的影响， 除了中链饱和脂肪酸 （MCSFA）， 其余类型的 SFA可使血压升高， SFA对血管功能中度有害， 随着摄入时间的延长， 乳制品导致血脂异常的风险将增大， 纯棕榈油和椰子油对降低血脂有帮助， 摄入SFA碳链的奇偶和长度不同的SFA， 罹患2型糖尿病的风险不同； 同时总结了SFA 对心血管疾病 （CVD） 患病风险的影响， 总体SFA的摄入会增加CVD的风险， 但不同食物有不同的影响， 富含SFA的椰子油会导致心肌纤维化， 乳制品尤其是奶酪的摄入可降低CVD的发病风险， 红肉对心血管健康中度有害。

关键词: 心血管疾病, 脂蛋白类, 脂肪酸类

Abstract: Abstract：There are different opinions on the role of saturated fatty acids (SFA) in cardiovascular diseases (CVD). The sources of food, the parity of the SFA carbon chain, and the chain length are major factors. This article reviews the effects of saturated fatty acids on cardiovascular risk factors. In addition to medium chain SFA (MCSFA), other types of SFA can increase blood pressure. SFA is moderately harmful to vascular function. The risk of dyslipidemia caused by dairy products increases with the prolongation of intake time. Pure palm oil and coconut oil are helpful in reducing blood lipids. SFA with different odd and even carbon chains and different lengths has different risks of developing type 2 diabetes. The effects of saturated fatty acids on the risk of CVD were summarized. Generally, SFA intake increases the risk of CVD, but specific foods have different effects. Coconut oil rich in SFA can cause myocardial fibrosis. Dairy products, especially cheese, can reduce the risk of CVD. Red meat is moderately harmful to cardiovascular health.

Key words: cardiovascular diseases, lipoproteins, fatty acids