Abstract: Abstract： Objective To evaluate the diagnostic accuracy of CMS50F for screening in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods Sixty-four volunteers with suspected OSAHS underwent simultaneous noc⁃ turnal polysomnography (PSG), micromovement sensitive mattress sleep monitoring system（MSMSMS） and CMS50F. The ap⁃ nea-hypopnea index (AHI) detected by PSG and MSMSMS was used as the diagnostic standard for OSAHS. The reliability of CMS50F for monitoring sleep was assessed. Results There was no statistic difference in CMS50F-ODI3 and PSG-AHI be⁃ tween normal, mild and moderate OSAHS groups（P > 0.05). The CMS50F-ODI3 was smaller than the PSG-AHI in severe OSAHS patients（P < 0.05). There was a positive correlation between CMS50F-ODI3 and PSG-AHI（r=0.855, P < 0.05). PSG-AHI≥5 events per hour was used as the threshold value to diagnose OSAHS, the sensitivity and specificity of CMS50F were 94.5% and 88.9%. There were no significant differences in CMS50F- ODI3 and MSMSMS -AHI between normal, mild and moderate OSAHS patients（P > 0.05). The value of CMS50F-ODI3 was smaller than MSMSMS-AHI in severe OSAHS patients (P < 0.05). There was also a significant correlation between CMS50F- ODI3 and MSMSMS -AHI (r=0.867， P < 0.05). MSMSMS -AHI≥5 events per hour was used as the threshold value to diagnose OSAHS, the sensitivity and specificity of CMS50F were 94.5% and 88.9%. Conclusion CMS50F can be used as a portable and reliable device for screening of pa⁃ tients suspected OSAHS.

Key words: sleep apnea, obstructive, polysomnography, monitoring, ambulatory, apnea-hypopnea index （AHI）, sensitivity, specificity