Abstract: Objective To evaluate the efficacy of jianshenxiaodao granule for children with functional dyspepsia (FD). Methods From December 2016 to November 2018, 120 patients met Rome IV criteria were enrolled and divided into jianshenxiaodao granule group and domperidone group. Clinical symptoms and electrogastrogram were observed before and after treatment in two groups. The clinical efficacy of two groups was compared after two-week treatment and two-week follow-up. Results There were no significant differences in the sex, age, duration of disease, number of basal symptoms including abdominal pain, anorexia, sour regurgitation, belchin, nausea and vomiting between two groups (P＞0.05). In the 2 groups after treatment (before meal and after meal), the gastric motility and the abnormal rate of gastric electrical rhythm were significantly decreased (P＜0.05). The total effective rate was better in observation group than that of control group (P＜0.05). Conclusion The jianshenxiaodao granule can significantly improve the clinical symptoms of children with FD,enhance the gastric motility and improve the clinical efficacy that lasts until 8 weeks after drug withdrawal, which is worthy of further clinical promotion.

Key words: dyspepsia, domperidone, electrogastrography, child, jianshenxiaodao granule