Tianjin Medical Journal ›› 2021, Vol. 49 ›› Issue (4): 441-444.doi: 10.11958/20201643

• Review • Previous Articles     Next Articles

Research progress of relaxin in atrial fibrillation

LI Rui-ling, ZHAO Zhi-qiang△   

  1. Department of Cardiology, the Second Hospital of Tianjin Medical University, Tianjin Institute of Cardiology, Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease, Tianjin 300211, China
  • Received:2020-06-11 Revised:2021-01-05 Published:2021-04-15 Online:2021-04-16
  • Contact: ZHAO Zhi-qiang E-mail:zzqzzqzhiqiang@163.com

Abstract: Atrial fibrillation (AF) is a common persistent arrhythmia. Its mechanism is still unclear, involving electrical remodeling, structural remodeling, inflammatory response, oxidative stress and many other aspects. Recent studies on relaxin (RLX) have shown that relaxin plays an important role in the cardiovascular system. This paper summarizes the potential role of RLX in AF and its related mechanisms, which provides a new way for the prevention and treatment of AF.

Key words: atrial fibrillation, relaxin, atrial remodeling, matrix metalloproteinases 

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