Tianjin Medical Journal ›› 2022, Vol. 50 ›› Issue (8): 878-882.doi: 10.11958/20212860

• Drug Clinical Evaluations • Previous Articles     Next Articles

Effects of different doses of dexamethasone on iliac fascia block of ropivacaine under ultrasound guidance

WANG Dan1(), ZHAO Lixia1, PENG Yaqi1, YUAN Dajiang1,2,Δ()   

  1. 1 School of Anesthesia, Shanxi Medical University, Taiyuan 030012, China
    2 Department of Intensive Care Unit, the Second Hospital of Shanxi Medical University
  • Received:2021-12-31 Revised:2022-02-21 Published:2022-08-15 Online:2022-08-12
  • Contact: YUAN Dajiang E-mail:1019784728@qq.com;yuandajiang@sina.com

Abstract:

Objective To investigate the blocking effects of different doses of dexamethasone combined with ropivacaine in iliac fascia space block (FICB) after total hip replacement (THA). Methods A total of 83 patients with THA were divided into the observation group 1 (n=27), the observation group 2 (n=28) and the control group (n=28) according to the random number table. All patients were performed FICB guided by ultrasound. The observation group 1, the observation group 2 and the control group were given 0.25% ropivacaine 100 mg combined with dexamethasone 5 mg, 10 mg and 0 mg, respectively. The duration of surgery and visual analog scale (VAS) scores at rest and exercise at 4, 8, 12, 24, 36 and 48 hours after local anesthetic injection were recorded. Quadriceps muscle strength scores at 8, 12, 24, 36, 48 hours after injection, analgesic pump pressing times and remedial analgesia times within 48 hours after injection were recorded. Results There were no significant differences in operation duration, VAS scores at 4, 8 and 48 hours between the three groups. At 12, 24 and 36 hours, the VAS scores during rest and exercise were significantly lower in the observation group 1 and the observation group 2 than those of the control group (P<0.05), and there were no significant differences in VAS scores during rest and exercise between the observation group 1 and the observation group 2. There were no significant differences in muscle strength grade 1-5 score composition at 8, 12, 24, 36 and 48 hours between the three groups. The ratio of 2 or more times of analgesic pump pressing and 1 or more times of remedial analgesia within 48 hours after operation were significantly lower in the observation group 1 and the observation group 2 compared with those of the control group (P<0.05), but there were no significant differences between the observation group 1 and the observation group 2. Conclusion The FICB analgesic effect of ropivacaine can be enhanced by dexamethasone 5 mg and 10 mg, but the inhibitory effect of quadriceps muscle strength is not increased.

Key words: Dexamethasone, nerve block, arthroplasty, replacement, hip, Ropivacaine

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