Tianjin Medical Journal

Tianjin Med J ›› 2015, Vol. 43 ›› Issue (4): 443-445.doi: 10.11958/j.issn.0253-9896.2015.04.030

• Review • Previous Articles     Next Articles

Review the connection between trimethylamine oxide and atherosclerosis

WANG Weizhan1,2, TIAN Fengshi2△   

  1. 1 The Fourth Center Clinical Institution of Tianjin Medical University, Tianjin 300140, China; 2 The Fourth Center Hospital of Tianjin
  • Received:2014-08-07 Revised:2014-12-10 Published:2015-04-15 Online:2015-04-13
  • Contact: TIAN Fengshi E-mail:472399227@qq.com

PDF (PC)

7582

Abstract: Abstract: Recent researches revealed that intestinal flora contribute to the development of metabolic syndrome, espe⁃ cially to the disorder of their targeted cardiovascular system. Blood cholesterol level is affected by the metabolism of intesti⁃ nal flora in cholesterol and bile acid. At the same time, the blood cholesterol level is the key player in development of athero⁃ sclerosis. This review mainly discussed the relationship between the intestinal flora dependent metabolite trimethylamine ox⁃ ide (Trimetlylamine oxide, TMAO) and atherosclerosis.

Key words: atherosclerosis, metabolic syndrome X, enterobacteriaceae, cardiovascular diseases, cholesterol, trimetlyl? amine oxide