Abstract: [Abstract]   Objective   To investigate the relationship of cardiopulmonary adverse events during6-minute walk test
(6MWT) with different lung function and cardiac complications in patients with chronic obstructive pulmonary disease
(COPD).  Methods   Eighty-five COPD patients who finished the test were divided into three groups according to their complications, consisted of COPD group（I，n=16), COPD + left ventricular diastolic dysfunction group （Ⅱ，n=31) and COPD + left ventricular diastolic dysfunction + chronic pulmonary heart disease group（Ⅲ，n=38). The values of heart rate (HR) and pulse oxygen saturation（SpO2）were compared between three groups before and after the test of6MWT,10mins after the test of 6MWT.Results There were27cases（31.76%）finished the test of 6MWT.  Results  showed there were abnormal heart rhythms in 19cases（22.35%) , SpO2<0.90in 14cases（16.47%) and HR >120bpm or SpO2<0.90in 15cases（17.65%). There were significant differences in HR before and after the tests between three groups（P<0.05). There were significant differences in SpO2 before and after the tests between group II and group III（P<0.05).   Conclusion   Severe COPD patients with left ventricular diastolic dysfunction and chronic pulmonary heart disease are more likely to occur cardiopulmonary adverse events during the test of6MWT, and the HR and SpO2are not easy to return to the level before the test.

Key words: Pulmonary Disease, Chronic Obstructive, heart rate, SpO2, 6MWT, adverse events