Role of Runx2in Breast Cancer

• 综述 • Previous Articles Next Articles

Role of Runx2in Breast Cancer

Yao TIAN

Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, Tianjin Medical UniversityTianjin 300060, China

Received:2013-12-10 Revised:2014-02-06 Published:2014-08-15 Online:2014-08-15
Contact: Yao TIAN

Yao TIAN. Role of Runx2in Breast Cancer[J]. .

Abstract

Abstract: 【Abstract】 Runx2 is a member of the RUNXX family of transcription factors, as one of the important factors involved in expression and participation in the regulation of mammary specific genes in the mammary gland.In this review, we will focus on the role of Runx2 in breast cancer.

Key words: breast neoplasms, DNA- binding proteins, transcription factors, receptors, estrogen, bone neoplasms, Runx2, 骨转移

[1]	GAO Pan, XIE Bingxin, ZHOU Zandong, LIU Tong. Promoting effect of circulating FGF23 on atrial fibrosis in chronic kidney disease [J]. Tianjin Medical Journal, 2024, 52(9): 917-923.
[2]	MAN Yi, XU Ya, HE Xiancheng, SONG Shaofeng, LIU Aiguo. Relationship between expression levels of EGFR, Ki-67, P53 and CTC and the prognosis of triple negative breast cancer [J]. Tianjin Medical Journal, 2024, 52(8): 862-867.
[3]	ZHU Gangming, DONG Yongde, ZHU Ruiting, TAN Yuanman, TAO Juan, LIU Xiao, CHEN Decheng, YANG Gai. The value of magnetic resonance relaxation time quantitative imaging in predicting molecular subtypes of invasive ductal carcinoma [J]. Tianjin Medical Journal, 2024, 52(7): 770-774.
[4]	CHEN Zhiyan, WU Qiuyuan, DENG Yuhua, ZHOU Dan. Status and application of organoid technology in breast cancer research [J]. Tianjin Medical Journal, 2024, 52(6): 668-672.
[5]	LIU Danyang, LI Yongtao, ZHANG Haiyan, LI Lin, LIU Yang, SHEN Lei. Effect of breast cancer cell conditioned medium on biological behavior of bone marrow mesenchymal stem cells [J]. Tianjin Medical Journal, 2024, 52(5): 454-458.
[6]	TIAN Jiayu, FENG Dan, HU Han, ZHANG Shuli, TONG Shengxiong, LI Shaojun. Mechanism of quercetin alleviating postherpetic neuralgia in rats by inhibiting MIP-1α/CCR1/CCR5 signaling pathway [J]. Tianjin Medical Journal, 2024, 52(3): 256-260.
[7]	XU Dan, LIU Xia, ZHONG Diansheng. Frst-line treatment of Zorifertinib in EGFR-mutant NSCLC with CNS metastases: a report of two cases [J]. Tianjin Medical Journal, 2024, 52(3): 315-318.
[8]	YI Na, XIAO Wen, TIAN Yuan, YUAN Lili. Mechanism of BMAL1 attenuating H₂O₂-induced cardiomyocyte injury [J]. Tianjin Medical Journal, 2024, 52(2): 119-123.
[9]	CHEN Junjie, XU Xuemei, LI Yan, FU Jinying. Effects of Bazhen Decoction combined with Baizhu Fuzi Decoction on glucose metabolism and estrogen levels in rats with polycystic ovary syndrome [J]. Tianjin Medical Journal, 2024, 52(2): 154-160.
[10]	LU Xinyi, DU Weipo, LI Jinggang, GUO Fangfang, ZHANG Xiaolei, LIU Jing. Correlation between serum miR-193a-3p, ATF5 levels and chemotherapy efficacy in patients with triple negative breast cancer [J]. Tianjin Medical Journal, 2024, 52(12): 1313-1316.
[11]	XIE Haoran, LI Yihao, LIU Cheng, XIA Yuting, QIU Shenglei, XIONG Bin, FENG Qizhen. Research of predictive factors of axillary lymph node metastasis in breast cancer under the context of DIP payment of medical insurance [J]. Tianjin Medical Journal, 2024, 52(11): 1193-1196.
[12]	LIU Haoying, SHI Tianwei. Progress of the aryl hydrocarbon receptor in inflammatory skin diseases [J]. Tianjin Medical Journal, 2024, 52(11): 1221-1225.
[13]	ZHANG Guixian, LIU Dawei, LI Wenchang, CAI Jun, ZONG Wenhui, LIU Hongbin, ZHAO Xiumei. Mechanism study of BOC2 alleviating SAP inflammatory damage by inhibiting N-formyl peptide/formyl peptide receptor pathway [J]. Tianjin Medical Journal, 2024, 52(10): 1031-1037.
[14]	WU Haixiao, MA Wenjuan, LI Zhijun, ZHANG Chao. Relationship between pectoralis muscle index and prognosis of breast cancer patients with bone metastases based on radiomics [J]. Tianjin Medical Journal, 2023, 51(9): 1007-1010.
[15]	WANG Lei, YANG Tao, GENG Licheng, SUN Tianwei. Research progress of endocannabinoid system for prevention and treatment of osteoporosis [J]. Tianjin Medical Journal, 2023, 51(9): 1020-1024.

Role of Runx2in Breast Cancer

Cite this article

PDF (PC)

Knowledge

Abstract

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments