Abstract: Objective To explore the differences and infection factors of adherence of pulmonary rehabilitation(PR) in different periods of chronic obstructive pulmonary disease(COPD) patients. Methods The 304 patients were randomly distributed into two groups,including stable COPD with PR group(n=178) which perform PR after exacerbation and remain stable for 12 weeks,and AECOPD with PR group(n=126) which perform PR instantly after acute phrase.The course of PR is 12 weeks According to the adherence definition(practical time of accompolish PR programm > 70% of that planned time),we divided into good time-adherence group(n=115) and bad time-adherence group(n=189).Comparison of practical-perform time of PR, proportion of good time-adherence and PR quitting between two groups.Basic data of patients were collected and analyzed and independ infection factors of adherence was analyszed through binary logistic regression.Results The practical-perform time of PR, proportion of good time-adherence in stable COPD with PR group were higher than AECOPD with PR group while the PR quitting proportion was lower than AECOPD with PR group.Compare with AECOPD PR group,the income level and 6MWD were hingher in stable COPD PR group;and the age,proportion of tabacco-exposed,MRC scores and CAT scores were lower in Stable COPD group.Older-age, tabacco-exposed, higher MRC and CAT scores are danger factors for PR adherence, while the higher income level and longer 6MWD are protective factor for PR time-adherence in patients with COPD(P<0.05）. Conclusion The time adherence of COPD patients who undergo pulmonary rehabilitation was disappointing,especially postexacerbation.Good adherence would be expected in younger age, non tabacco-exposed, higher income level and better health-related quality of life.

Key words: pulmonary disease, chronic obstructive, rehabilitation, patient compliance, Logistic models, exacerbation