Abstract: Objective To investigate the preoperative risk factors of postoperative atrial fibrillation (POAF) in patients undergoing off-pump coronary artery bypass grafting (CABG). Methods A total of 1 888 patients underwent off-pump CABG in our hospital were divided into new onset atrial fibrillation group (POAF group, n=389) and non AF group (NPOAF group, n=1 499). Univariate analysis was used to compare general clinical data, preoperative biochemical indicators, preoperative echocardiography, coronary artery disease and preoperative medication between two groups. The indicators with statistically significant differences were further analyzed by Logistics regression analysis. Results The incidence of POAF was 20.60% (389 / 1 888). The data of age, chronic obstructive pulmonary disease (COPD) history, myocardial infarction history, preoperative urea nitrogen (BUN) level, left atrial diameter (LAD) and left ventricular end diastolic diameter (LVEDD) were higher in POAF group than those of NPOAF group, and the preoperative HYHA grading was lower in POAF group than that of NPOAF group（P＜0.05). The proportion of preoperative use of beta blockers was significantly lower in POAF group than that of NPOAF group (P＜0.01). Logistic regression analysis showed that increased age and LAD were independent preoperative risk factors for POAF. Preoperative beta blocker application was a protective factor for POAF. Conclusion It suggests that age, LAD and preoperative beta blocker application are related to the occurrence of POAF in patients underwent off-pump CABG.

Key words: coronary artery bypass, off-pump, postoperative new atrial fibrillation, risk factors, preoperative