Abstract: Abstract: Post-cardiac injury syndrome (PCIS) refers to a group of syndromes with hydropericardium, pleural effusion and pulmonary parenchyma inflammation as the main manifestation after heart injury. This paper reported a 41 years old male patient with acute myocardial infarction who developed high fever, bilateral pleural effusion, hydropericardium and other clinical manifestation after coronary stent implantation. The patient’s clinical symptoms improved after hormone treatment in the hospital. One month later, the patient reappeared the above symptoms. After hormone treatment again and reasonable adjustment of hormone dosage, the patient recovered well and no abnormality was found in the follow-up. This paper summarizes the clinical manifestations, diagnosis and treatment of the disease, in order to improve the clinicians’ understanding of the disease.

Key words: myocardial infarction, methylprednisolone, recurrence, post-cardiac injury syndrome, multiple serous
effusion