Tianjin Medical Journal ›› 2023, Vol. 51 ›› Issue (4): 441-444.doi: 10.11958/20221298

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Research progress on the relationship between high fat diet and cognitive impairment

LI Xiaoxiao1(), BAI Yanjie2,*(), WANG Yan1, ZHANG Yongchuang1, CHEN Limin1, CHEN Shuying1   

  1. 1 Henan University of Chinese Medicine, Zhengzhou 450046, China
    2 The First Affiliated Hospital of Henan University of Chinese Medicine
  • Received:2022-08-19 Revised:2022-11-21 Published:2023-04-15 Online:2023-04-20
  • Contact: BAI Yanjie E-mail:1173987953@qq.com;baiyj66@126.com

Abstract:

Cognitive impairment refers to one or more impairments in feeling, learning and memory, speech, attention and execution, which seriously affects the quality of life of patients. Studies have shown that high fat diet (HFD) can cause neuronal damage and cerebrovascular dysfunction, thus causing cognitive impairment. This article reviews the relevant mechanisms and treatment progress of HFD induced cognitive impairment, with a view to providing new ideas for effective prevention and treatment of cognitive impairment.

Key words: cognition disorders, diet, high-fat, neuritis, insulin resistance, synapses, oxidative stress

CLC Number: