Abstract: Abstract Objectives：To investigate the characteristics of recrurrent myocardial infarction(MI) and the influences of prior MI on the outcomes of patients with myocardial reinfarction(Re-MI). Method: The current data came from the Korea Acute Myocardial Infarction Registry (KAMIR) study, which consisted of consecutive acute MI patients survived from 10 major PCI centers in Korea from November 2005 to April 2008. 10,384 patients survived from hospitals were enrolled, among which 934 (8.99%) patients presented with Re-MI. We investigated the clinical outcomes between Re-MI patients and those with first-onset of MI (first-AMI group, n=9450) within 12-month followup.Results: The baseline characteristics are largely unfavorable in Re-MI group over first-AMI group. Patients in Re-MI group are older than those in first-AMI group (63.91±12.48 vs 62.54±12.56 years，p<0.05) with worse cardiac function(KillipIII/IV, 17.77% vs 10.28%，p<0.05), more prior revascularization history(p<0.001). Angiographic findings also demonstrate unfavorable characters in Re-MI group, such as more multivessle disease(p<0.001), less successful PCI results(p<0.001),et al. Patients with prior MI have worse clinical outcomes than first-AMI group in 12-month mace(ORunadjusted:1.481, 95% CI: 1.222-1.796, P<0.001) even after adjusted by age, killip’s grade, treatment et al(ORadjusted:1.409, 95% CI: 1.114-1.782, P<0.01).Conclusion: Patients with recurrent MI presented with worse baseline characteristics and more severe coronary artery conditions, which might lead to insufficient revascularization and relate to a higher risk of MACE on 1year followup.

Key words: Acute myocardial infarction, Revascularization, Percutaneous coronary intervention, Prognosis, Recurrent myocardial infarction