天津医药

天津医药 ›› 2019, Vol. 47 ›› Issue (4): 428-430.doi: 10.11958/20190155

• 临床研究 • 上一篇    下一篇

原发性卵巢恶性黑色素瘤合并成熟性畸胎瘤一例并文献复习

李美月，田文艳，张旭红，闫晔，盛燕，郭飞，王颖梅△，薛凤霞   

  1. 天津医科大学总医院妇产科（邮编300052）
  • 收稿日期:2019-01-17 修回日期:2019-03-14 出版日期:2019-04-15 发布日期:2019-05-27
  • 通讯作者: 王颖梅 E-mail:wangyingmei1978@126.com
  • 作者简介:李美月（1990），女，硕士在读，主要从事妇科肿瘤研究
  • 基金资助:
    国家自然科学基金;国家自然科学基金

Primary malignant melanoma of ovarian mature teratoma: a case report and literature review

LI Mei-yue, TIAN Wen-yan, ZHANG Xu-hong, YAN Ye, SHENG Yan, GUO Fei, WANG Ying-mei△, XUE Feng-xia   

  1. Department of Gynecology and Obstetrics, Tianjin Medical University General Hospital, Tianjin 300052, China
  • Received:2019-01-17 Revised:2019-03-14 Published:2019-04-15 Online:2019-05-27
  • Supported by:
    Natural Science Foundation of China;Natural Science Foundation of China

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摘要： 原发性卵巢恶性黑色素瘤临床罕见，恶性程度高、预后差。本文回顾性分析了1例原发性卵巢恶性黑色素 瘤合并成熟性畸胎瘤病例，患者表现为腹胀，盆腔核磁示盆腔内可见巨大囊实性肿块，盆腹腔大量积液。给予手术 处理，病理证实为原发性卵巢恶性黑色素瘤伴成熟性畸胎瘤，随访4个月，患者因多器官功能衰竭死亡。同时复习了 该病相关文献资料，以提高对本病的认识。

关键词: 卵巢肿瘤, 黑色素瘤, 原发性, 诊断, 鉴别, 预后, 治疗, 畸胎瘤

Abstract: Primary malignant melanoma of ovary is rare clinically, with high malignancy and poor prognosis. This article retrospectively analyzed a case of primary ovarian malignant melanoma with mature teratoma. The patient showed abdominal distension, and the pelvic magnetic resonance imaging showed a large cystic solid mass in the pelvic cavity, and a large amount of fluid in the pelvic and abdominal cavity. Surgical treatment was given. Histopathological result was confirmed as primary ovarian malignant melanoma with mature teratoma. The patient died of multiple orgon failure after 4 months of followed-up. This paper reviewed the relevant literature to improve the understanding of the disease.

Key words: ovarian neoplasms, melanoma, primary, diagnosis, differential, prognosis, therapy, teratoma