Abstract:

Abstract: Objective To explore the diagnostic value of contrast-enhanced ultrasound (CEUS) in detecting small liver
metastasis (SLM) from breast cancer. Methods A total of 92 cases diagnosed as breast cancer by surgical pathology and
suspected SLM by conventional ultrasonography were included in this study. CEUS was used to check liver lesion in
patients. The biopsy operation was used as the gold standard. The coincidence rate of benign and malignant pathology was
used to compare the consistency between CEUS and biopsy pathology. Results In 92 cases suspected liver metastases of
breast cancer by routine ultrasound, there were 54 cases were diagnosed as benign by pathology, and all 92 cases were
diagnosed as benign by CEUS. Thirty- eight cases were diagnosed as metastasis by pathology, in which 36 cases were
correctly diagnosed by CEUS. The sensitivity of CEUS for the diagnosis of liver metastases of breast cancer was 94.74 % (36/
38), specificity was 100% (54/54), positive predictive value (PPV) was 100% (36/36) and negative predictive value (NPV) was
96.43% (54/56). Conclusion CEUS has a higher diagnostic value in SLM of breast cancer, and has clinical practical value.

Key words: ultrasonography, breast neoplasms, neoplasm metastasis, acoustic contrast