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Effect of metabolic syndrome on left ventricular function after acute myocardial infarction

  

  • Received:2011-06-07 Revised:2012-01-01 Published:2012-08-15 Online:2012-08-15

Abstract: Objective To investigate the effect of metabolic syndrome on left ventricular function after AMI onset. Methods We prospectively studied the relationship between metabolic syndrome and left ventricular function in 161 patients with AMI. Patients were grouped to metabolic syndrome group(n=86)and non metabolic syndrome group(n=75). left ventricular end diastolic volume (LVEDV) and LVEF were measured at admission and at 30 days after AMI onset. Results 56.4%of the 161 AMI patients were complicated with MS. Compared with non MS group, LVEDV of MS were increased (for admission: 139.5ml±41.3ml vs.124.4ml±36.9ml,P=0.016; for 30 days: 154.1ml±40.8ml vs.139.1ml±36.3ml,P=0.016),and There was no difference in LVEF between the 2 groups(for admission: 49.4%±7.2% vs.50.4%±8.3%,P=0.377; for 30 days: 52.5%±6.8% vs.54.3% ±8.3%,P=0.119). Conclusions There were high prevalence of MS in patients with AMI, and there were not significant effect of MS on left ventricular function after AMI onset.

Key words: myocardial infarction, metabolic syndrome, left ventricular ejection fraction