Abstract:

[Abstract] Objective To analyze the current clinic application of severe acne treatment, and to provide evidences to improve its treatment. Methods Using sampling survey, a total of3012severe acne patients who visited the dermato? logical department of 35hospitals over the country for the first time were selected for this study. Each patient filled a ques? tionnaire about their acknowledgement, history of medical intervention and drug therapy of severe acne. Results Among all3012patients with severe acne,76.6% believed acne is a kind of skin disease, but only35.2% of the patients went to see doctors at early stage of disease, while others choose interventions such as self-extrudation , topical medication or skin care products, herbal tea /folk recipes, beauty salons and application of coverture cosmetics. Among all severe acne patients, 2388cases (79.3%）had taken oral medications, which included1161(48.6%) patients who took anti-biotics.394cases (33.9%) took roxithromycine and173cases(14.9%) took other kinds of anti-biotics.55.5% of all these patients who took oral medication less than4weeks in duration.2081cases (69.1%) applied external drugs, in which includes90cases (4.3%) of using glucocorticoid, and437cases (21.0%) of using other kinds of external products. The adverse effects of topical treat? ments were commonly observed, such as erythema (512cases,24.6%), desquamation (683cases,32.8%), scab (73cases, 3.5%) and hypersensitive (281cases,13.5%).Conclusion Severe acne is a disease need systematic treatment. but only mi? nority of the patients went to see doctors at early stage of disease. The current problems in treatment of severe acne include lack of target in choosing drugs, not long enough treatment course, and adverse effects of cutaneous administration.Early , safe and targeted medical attention with sufficient treatment course is encouraged.

Key words: acne, vulgaris, anti-bacterial agents, administration, cutaneous, adverse effects