Tianjin Med J ›› 2015, Vol. 43 ›› Issue (10): 1209-1212.doi: 10.11958/j.issn.0253-9896.2015.10.033

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Research of platelets activation during Inflammation

  

  1. 1 Department of Otolaryngology, Tianjin Medical University General Hospital, Tianjin 300052, China; 2 Medical Laboratory
  • Received:2015-02-28 Revised:2015-07-20 Published:2015-10-15 Online:2015-10-22

Abstract: Abstract: Platelets is the important hemostatic component in the blood and the critical participants in inflammation.
It is an important promoting factor during inflammation and can recruit leukocytes and aggregate in sepsis. Decreasing plate⁃
let count was correlated with reverse clinical outcome. Therefore, the value of the platelets examination in clinical monitor
was studied by many researchers. Under circumstance of fungal infections, platelets mediate antimicrobial activity and assist
dissemination of the fungi synchronously. Regulating interaction between platelets and fungi is difficult. In allergic inflamma⁃
tion patients, the excessive activating of platelets aggravates airway obstruction and worsen pulmonary function. We reviewed
current research in activating platelets during inflammation.

Key words: platelet activation, inflammation, sepsis, fungi, asthma, review