Tianjin Med J ›› 2016, Vol. 44 ›› Issue (2): 234-236.doi: 10.11958/20150136

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Renal sympathetic denervation for the treatment of hypertensive heart disease with systolic heart failure

XIA Dasheng, LU Chengzhi, WANG Li   

  1. Department of Cardiology of Tianjin First Center Hospital, Tianjin 300192,China
  • Received:2015-08-31 Revised:2015-10-29 Published:2016-02-15 Online:2016-02-15

Abstract: Objective To evaluate the effectiveness of renal sympathetic denervation (RDN) for hypertensive heart dis⁃ ease combined with systolic heart failure. Methods Two patients (mean age 35 years) with hypertensive heart disease combined with systolic heart failure on maximal tolerated heart failure therapy underwent bilateral renal denervation. Echocardiography, the six minute walk distance, renal function, glycosylated hemoglobin and NT-proBNP were assessed at baseline and 1 year after renal denervation. Results Renal artery angiography showed that no stenosis and dissection. After 1 year follow up, the left ventricular ejection fraction (LVEF), six minute walk distance and NT- proBNP were significantly improved, and the size of left ventricular decreased. Conclusion RDN is effective and feasible for the treatment in patients with hypertensive heart disease and systolic heart failure.

Key words: renal sympathetic denervation, systolic heart failure, hypertension