Tianjin Medical Journal

Tianjin Med J ›› 2016, Vol. 44 ›› Issue (4): 404-407.doi: 10.11958/20150383

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Research advances in biomarkers of the prognosis of breast cancer

HAN Lu, SONG Fengju, CHEN Kexin△   

  1. Department of Epidemiology and Biostatistics, Tianjin Medical University Cancer Institute and Hosipital, National Clinical Research Center for Cancer, Key Laboratory of Breast Cancer Prevention and Therapy, Tianjin 300060, China
  • Received:2015-12-08 Revised:2016-01-08 Published:2016-04-15 Online:2016-05-20
  • Contact: △Corresponding Author E-mail: chenkexin@tjmuch.com E-mail:chenkexin1963@yahoo.com

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Abstract: Abstract： Breast cancer has become the most common malignant tumor and the major cause of cancer-related death for women around the world. The number of patients shows an increasing trend recently. Breast cancer is a big threaten to wom⁃ en’ s health and quality of life. With the development of molecular biology, molecular biomarkers have been found assiciated with prognosis in patients with breast cancer, which makes it possible to predict cancer patient survival precisely and practi⁃ cally. This review summarized those new developments of biomarkers on the prognosis of breast cancer.

Key words: breast neoplasms, prognosis, biological markers, review, miRNA-21, miRNA-210, C-X-C chemokine receptor type 4, aldehyde dehydrogenase 1 family, member A1, B-cell lymphoma-2, BRCA1/BRCA2