Abstract: Abstract: Podocytic infolding glomerulopathy (PIG) is a rare glomerular disease found in recent years. Its diagnosis mainly depends on pathological features. At present, there are relatively few clinical cases of this disease. This paper introduces a case of PIG caused by chemotherapy of malignant lymphoma. A 46-year-old female patient showed positive proteinuria and mild edema of lower limbs after chemotherapy for diffuse large B lymphoma. The related experimental data were in accordance with the diagnosis of nephrotic syndrome. The renal biopsy was performed. The pathological diagnosis was in consistent with PIG. The purpose of this article was to analyze the pathogenesis of PIG and review the clinical reports of PIG.

Key words: podocytic infolding glomerulopathy, after chemotherapy for lymphoma, podocyte injury, complement activation