Abstract: Objective　To explore the value of 3D-STI in evaluating the severity of coronary artery disease, left ventricular wall motion and left ventricular function in elderly non-ST-segment elevation myocardial infarction (NSTEMI) patients with chronic renal insufficiency. Methods　A total of 128 elderly NSTEMI patients were collected. According to renal function, patients were divided into renal insufficiency group and normal group. Clinical characteristics, global longitudinal strain (GLS), global radial strain (GRS), global circumferential strain (GCS), global area strain (GAS) and coronary artery disease SYNTAX scores were compared between the two groups. Results　Compared with normal group, the GLS, GRS, GCS, GAS, and LVEF were significantly decreased in the renal insufficiency group (P＜0.05). Compared with the normal group,SYNTAX scores were significantly higher in coronary artery lesion group, and there were more three vessel lesions in this group. There were significantly higher NT-proBNP and hs-CRP in coronary artery lesion group (P＜0.01).SYNTAX score was negatively correlated with GLS, GCS, GRS, GAS and left ventricular ejection fraction (r=-0.472, -0.477, -0.528, -0.306, P＜0.01). The left ventricular ejection fraction was positively correlated with GLS, GCS, GRS and GAS (r=    0.423, 0.316, 0.413, 0.403, P＜0.01). Conclusion　The 3D-STI can be used as a new technique to evaluate the degree of coronary artery lesions, left ventricular wall motion and left ventricular function in elderly NSTEMI patients with chronic renal insufficiency, and provide reference for early clinical evaluation and treatment.

Key words: non-ST elevated myocardial infarction, renal insufficiency, chronic, echocardiography, three-dimensional, aged, three-dimensional speckle tracking imaging