Tianjin Medical Journal ›› 2023, Vol. 51 ›› Issue (9): 968-971.doi: 10.11958/20230001
• Experimental Research • Previous Articles Next Articles
WANG Jinxiang1(), XU Guowu1, JIN Heng1, HE Bin2, CHAI Yanfen1,△(
)
Received:
2023-01-05
Revised:
2023-04-18
Published:
2023-09-15
Online:
2023-09-13
Contact:
△E-mail:WANG Jinxiang, XU Guowu, JIN Heng, HE Bin, CHAI Yanfen. Effects of mild hypothermia treatment on coagulation function and inflammatory factors in a swine model after cardiac arrest and extracorporeal cardiopulmonary resuscitation[J]. Tianjin Medical Journal, 2023, 51(9): 968-971.
CLC Number:
组别 | 体质量/ kg | 中心体温/ ℃ | 心率/ (次/min) | 平均动脉 压/mmHg | 呼吸频率/ (次/min) |
---|---|---|---|---|---|
对照组 | 38.8±2.3 | 37.2±0.2 | 112±8 | 104±5 | 15±2 |
常温组 | 39.3±2.4 | 37.1±0.2 | 109±7 | 107±7 | 16±3 |
亚低温组 | 38.7±2.2 | 37.3±0.3 | 113±9 | 105±5 | 15±3 |
F | 0.117 | 1.059 | 0.402 | 0.424 | 0.273 |
Tab.1 Comparison of basic parameters before experiment between the three groups
组别 | 体质量/ kg | 中心体温/ ℃ | 心率/ (次/min) | 平均动脉 压/mmHg | 呼吸频率/ (次/min) |
---|---|---|---|---|---|
对照组 | 38.8±2.3 | 37.2±0.2 | 112±8 | 104±5 | 15±2 |
常温组 | 39.3±2.4 | 37.1±0.2 | 109±7 | 107±7 | 16±3 |
亚低温组 | 38.7±2.2 | 37.3±0.3 | 113±9 | 105±5 | 15±3 |
F | 0.117 | 1.059 | 0.402 | 0.424 | 0.273 |
组别 | PT/s | APTT/s | TT/s | FIB/(g/L) | D-D/ (mg/L) |
---|---|---|---|---|---|
对照组 | 18.8±3.4 | 35.5±4.1 | 15.2±2.7 | 5.3±1.6 | 0.9±0.4 |
常温组 | 40.5±7.2a | 72.8±6.6a | 36.5±7.1a | 13.4±5.5a | 2.6±1.3a |
亚低温组 | 26.7±5.9ab | 54.2±8.7ab | 22.6±4.3ab | 9.7±3.4ab | 1.7±0.5ab |
F | 22.108** | 46.015** | 27.628** | 6.671* | 6.200* |
Tab.2 Comparison of coagulation function indexes between the three groups
组别 | PT/s | APTT/s | TT/s | FIB/(g/L) | D-D/ (mg/L) |
---|---|---|---|---|---|
对照组 | 18.8±3.4 | 35.5±4.1 | 15.2±2.7 | 5.3±1.6 | 0.9±0.4 |
常温组 | 40.5±7.2a | 72.8±6.6a | 36.5±7.1a | 13.4±5.5a | 2.6±1.3a |
亚低温组 | 26.7±5.9ab | 54.2±8.7ab | 22.6±4.3ab | 9.7±3.4ab | 1.7±0.5ab |
F | 22.108** | 46.015** | 27.628** | 6.671* | 6.200* |
组别 | TNF-α | IL-6 |
---|---|---|
对照组 | 143.5±6.2 | 51.3±4.7 |
常温组 | 370.8±14.3a | 182.6±12.5a |
亚低温组 | 257.3±7.4ab | 103.4±9.6ab |
F | 780.993** | 290.870** |
Tab.3 Comparison of expression levels of inflammatory factors between the three groups
组别 | TNF-α | IL-6 |
---|---|---|
对照组 | 143.5±6.2 | 51.3±4.7 |
常温组 | 370.8±14.3a | 182.6±12.5a |
亚低温组 | 257.3±7.4ab | 103.4±9.6ab |
F | 780.993** | 290.870** |
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