
Tianjin Medical Journal ›› 2026, Vol. 54 ›› Issue (3): 299-302.doi: 10.11958/20252617
• Applied Research • Previous Articles Next Articles
LI Ming1(
), JIN Jianhua1, WU Jianting1, WANG Junhui1, XU Jun2,△(
)
Received:2025-07-31
Revised:2025-10-29
Published:2026-03-15
Online:2026-03-17
Contact:
E-mail:LI Ming, JIN Jianhua, WU Jianting, WANG Junhui, XU Jun. The impact of combined fixation with personalized lumbar cushions and body membranes on the positioning accuracy and stability of patients with cervical cancer undergoing radiotherapy[J]. Tianjin Medical Journal, 2026, 54(3): 299-302.
CLC Number:
| 组别 | 年龄/岁 | 膀胱尿量/mL | BMI/(kg/m2) |
|---|---|---|---|
| 对照Ⅰ组 | 55.4±9.3 | 291.9±123.4 | 21.2(18.8,26.9) |
| 对照Ⅱ组 | 52.8±11.0 | 226.2±128.0 | 21.4(19.0,26.3) |
| 试验组 | 51.4±8.2 | 247.6±120.6 | 20.0(17.0,24.5) |
| F或H | 1.045 | 1.753 | 2.410 |
Tab.1 Comparison of general clinical data of the three groups of patients
| 组别 | 年龄/岁 | 膀胱尿量/mL | BMI/(kg/m2) |
|---|---|---|---|
| 对照Ⅰ组 | 55.4±9.3 | 291.9±123.4 | 21.2(18.8,26.9) |
| 对照Ⅱ组 | 52.8±11.0 | 226.2±128.0 | 21.4(19.0,26.3) |
| 试验组 | 51.4±8.2 | 247.6±120.6 | 20.0(17.0,24.5) |
| F或H | 1.045 | 1.753 | 2.410 |
| 组别 | n | X轴 | Y轴 | Z轴 |
|---|---|---|---|---|
| 对照Ⅰ组 | 24 | 2.73±1.26 | 2.75±1.19 | 2.10±1.23 |
| 对照Ⅱ组 | 24 | 2.18±1.15 | 2.74±1.35 | 2.40±1.24 |
| 试验组 | 24 | 2.00±1.13 | 1.93±0.86ab | 1.69±1.09 |
| F | 2.443 | 4.724* | 2.122 |
Tab.2 Comparison of positioning and translation errors between the three groups
| 组别 | n | X轴 | Y轴 | Z轴 |
|---|---|---|---|---|
| 对照Ⅰ组 | 24 | 2.73±1.26 | 2.75±1.19 | 2.10±1.23 |
| 对照Ⅱ组 | 24 | 2.18±1.15 | 2.74±1.35 | 2.40±1.24 |
| 试验组 | 24 | 2.00±1.13 | 1.93±0.86ab | 1.69±1.09 |
| F | 2.443 | 4.724* | 2.122 |
| 组别 | n | X轴 | Y轴 | Z轴 |
|---|---|---|---|---|
| 对照Ⅰ组 | 24 | 1.32±0.63 | 0.90±0.67 | 1.07±0.66 |
| 对照Ⅱ组 | 24 | 0.87±0.57 | 1.10±0.74 | 1.29±0.83 |
| 试验组 | 24 | 0.74±0.65a | 0.98±0.61 | 0.90±0.65 |
| F | 6.005* | 0.493 | 1.834 |
Tab.3 Comparison of positioning rotation errors between the three groups
| 组别 | n | X轴 | Y轴 | Z轴 |
|---|---|---|---|---|
| 对照Ⅰ组 | 24 | 1.32±0.63 | 0.90±0.67 | 1.07±0.66 |
| 对照Ⅱ组 | 24 | 0.87±0.57 | 1.10±0.74 | 1.29±0.83 |
| 试验组 | 24 | 0.74±0.65a | 0.98±0.61 | 0.90±0.65 |
| F | 6.005* | 0.493 | 1.834 |
| 组别 | X轴 | Y轴 | Z轴 |
|---|---|---|---|
| 对照Ⅰ组 | 68.4(59.1,78.4) | 68.7(60.3,78.2) | 66.0(59.4,74.8) |
| 对照Ⅱ组 | 68.4(59.6,76.5) | 69.2(60.1,74.6) | 68.9(58.0,76.1) |
| 试验组 | 61.9(53.8,65.0)ab | 70.0(56.4,65.3)ab | 62.8(54.2,66.1) |
| H | 8.030* | 9.601* | 5.603 |
Tab.4 Comparison of coefficient of variation of displacement error between the three groups
| 组别 | X轴 | Y轴 | Z轴 |
|---|---|---|---|
| 对照Ⅰ组 | 68.4(59.1,78.4) | 68.7(60.3,78.2) | 66.0(59.4,74.8) |
| 对照Ⅱ组 | 68.4(59.6,76.5) | 69.2(60.1,74.6) | 68.9(58.0,76.1) |
| 试验组 | 61.9(53.8,65.0)ab | 70.0(56.4,65.3)ab | 62.8(54.2,66.1) |
| H | 8.030* | 9.601* | 5.603 |
| 组别 | X轴 | Y轴 | Z轴 |
|---|---|---|---|
| 对照Ⅰ组 | 68.5(59.6,75.5) | 67.9(60.1,76.6) | 68.1(58.5,76.7) |
| 对照Ⅱ组 | 69.7(56.6,76.9) | 67.9(57.5,74.8) | 67.8(58.5,74.8) |
| 试验组 | 62.1(55.1,65.6)b | 62.5(51.6,66.7) | 63.1(53.1,68.0) |
| H | 7.502* | 6.167 | 5.563 |
Tab.5 Comparison of coefficient of variation of positioning rotation error between the three groups
| 组别 | X轴 | Y轴 | Z轴 |
|---|---|---|---|
| 对照Ⅰ组 | 68.5(59.6,75.5) | 67.9(60.1,76.6) | 68.1(58.5,76.7) |
| 对照Ⅱ组 | 69.7(56.6,76.9) | 67.9(57.5,74.8) | 67.8(58.5,74.8) |
| 试验组 | 62.1(55.1,65.6)b | 62.5(51.6,66.7) | 63.1(53.1,68.0) |
| H | 7.502* | 6.167 | 5.563 |
| [1] | CARVALHO H A, MAURO G P. History of radiotherapy in the treatment of uterine cervix cancer:an overview[J]. Rev Assoc Med Bras(1992), 2023, 69(suppl 1):e2023S126. doi:10.1590/1806-9282.2023S126. |
| [2] | WANG G, CHEN Y, WANG Z, et al. A prospective single-arm study of daily online adaptive radiation therapy for cervical cancer with reduced planning target volume margin:acute toxicity and dosimetric outcomes[J]. Int J Radiat Oncol Biol Phys, 2025, 122(4):1002-1011. doi:10.1016/j.ijrobp.2025.03.051. |
| [3] | LI Z, CHENG Y, DONG J, et al. The impact of setup errors on dose distribution in cervical cancer radiotherapy and the margin from CTV to PTV[J]. J Cancer Res Clin Oncol, 2024, 150(12):516. doi:10.1007/s00432-024-06032-6. |
| [4] | 梁广立, 杜武, 蒋胜鹏, 等. 乳腺癌保乳术后调强放疗影像引导技术的研究进展[J]. 国际医学放射学杂志, 2023, 46(4):462-467. |
| LIANG G L, DU W, JIANG S P, et al. Research progress on image-guided radiotherapy after breast-conserving surgery for breast cancer[J]. Int J Med Radiol, 2023, 46(4):462-467. doi:10.19300/j.2023.Z20065. | |
| [5] | LI Y, SUN W, LIU S, et al. Effect of body contour changes on the setup and dosimetric accuracy of radiotherapy after cervical cancer surgery[J]. Front Oncol, 2024, 14:1392741. doi:10.3389/fonc.2024.1392741. |
| [6] | MAHANTSHETTY U, NAGA P, NACHANKAR A, et al. Set-up errors,organ motion,tumour regression and its implications on internal target volume-planning target volume during cervical cancer radiotherapy: results from a prospective study[J]. Clin Oncol (R Coll Radiol), 2022, 34(3):189-197. doi:10.1016/j.clon.2021.10.010. |
| [7] | SUN H, LIU Y, YUAN L, et al. Dosimetry study of Auto-VMAT planning and Manual-VMAT planning based on Pinnacle3 9.10 in radiotherapy for cervical cancer[J]. Medicine (Baltimore), 2023, 102(26):e34129. doi:10.1097/MD.0000000000034129. |
| [8] | DENG J. Effects of anxiety and depression on positioning error of radiotherapy[J]. International Journal of Frontiers in Medicine, 2024, 6(3):56-61. doi:10.25236/IJFM.2024.060309. |
| [9] | HUANG S, MAI X, LIU H, et al. Plan quality and treatment efficiency assurance of two VMAT optimization for cervical cancer radiotherapy[J]. J Appl Clin Med Phys, 2023, 24(10):e14050. doi:10.1002/acm2.14050. |
| [10] | WANG Y, SUN Y, GAN K, et al. Bone marrow sparing oriented multi-model image registration in cervical cancer radiotherapy[J]. Comput Biol Med, 2023, 166:107581. doi:10.1016/j.compbiomed.2023.107581. |
| [11] | CHANG Y, LIANG Y, YANG B, et al. Dosimetric comparison of deformable image registration and synthetic CT generation based on CBCT images for organs at risk in cervical cancer radiotherapy[J]. Radiat Oncol, 2023, 18(1):3. doi:10.1186/s13014-022-02191-3. |
| [12] | WANG G, WANG Z, GUO Y, et al. Evaluation of PTV margins with daily iterative online adaptive radiotherapy for postoperative treatment of endometrial and cervical cancer:a prospective single-arm phase 2 study[J]. Radiat Oncol, 2024, 19(1):2. doi:10.1186/s13014-023-02394-2. |
| [13] | LEI Y, CHAO M, YANG K, et al. A novel network architecture for post-applicator placement CT auto-contouring in cervical cancer HDR brachytherapy[J]. Med Phys, 2025, 52(7):e17908. doi:10.1002/mp.17908. |
| [14] | 李雅宁, 林承光, 杨鑫. 体质量指数对宫颈癌调强放疗摆位误差影响[J]. 中华放射肿瘤学杂志, 2021, 30(2):186-190. |
| LI Y N, LIN C G, YANG X. Effects of body mass index on positioning errors in intensity-modulated radiotherapy for cervical cancer[J]. Chinese Journal of Radiation Oncology, 2021, 30(2):186-190. doi:10.3760/cma.j.cn113030-20191014-00420. | |
| [15] | 伍嘉颖, 陆世培, 李存啸, 等. 盆腔肿瘤放疗执行前膀胱充盈一致性研究[J]. 中华放射肿瘤学杂志, 2021, 30(1):61-65. |
| WU J Y, LU S P, LI C X, et al. Study on bladder filling consistency before pelvic tumor radiotherapy[J]. Chinese Journal of Radiation Oncology, 2021, 30(1):61-65. doi:10.3760/cma.j.cn113030-20190624-00245. | |
| [16] | VALENCIA LOZANO I, BUSS E, SPINA C S, et al. Quantification and dosimetric impact of intra-fractional bladder changes during CBCT-guided online adaptive radiotherapy for pelvic cancer treatments[J]. J Appl Clin Med Phys, 2025, 26(6):e70074. doi:10.1002/acm2.70074. |
| [17] | 马平平, 伍海彪, 叶芝甫, 等. 体膜固定宫颈癌55例放疗腹部皮下脂肪厚度与体积对摆位误差影响[J]. 中华肿瘤防治杂志, 2020, 27(13):108-110. |
| MA P P, WU H B, YE Z F, et al. Effects of abdominal subcutaneous fat thickness and volume on positioning error in 55 cases of radiotherapy for cervical cancer with plastic film fixation[J]. Chinese Journal of Cancer Prevention and Treatment, 2020, 27(13):108-110. doi:10.16073/j.cnki.cjcpt.2020.13.11. | |
| [18] | 林志悦, 许晨迪, 李宗泰, 等. 基于一体化CT直线加速器图像引导放疗的宫颈癌不同体位固定方式的对比研究[J]. 中华肿瘤防治杂志, 2023(15):932-936. |
| LIN Z Y, XU C D, LI Z T, et al. A comparative study on different positioning fixation methods for cervical cancer radiotherapy guided by integrated CT linear accelerator[J]. Chinese Journal of Cancer Prevention and Treatment, 2023(15):932-936. doi:10.16073/j.cnki.cjcpt.2023.15.06. | |
| [19] | 许森奎, 方键蓝, 肖亮杰, 等. 两种体位固定方法在宫颈癌调强放射治疗中摆位固定精度的差异研究[J]. 中华肿瘤防治杂志, 2022, 29(3):213-216. |
| XU S K, FANG J L, XIAO L J, et al. Study on the difference of positioning accuracy between two fixed methods in cervical cancer intensity-modulated radiotherapy[J]. Chinese Journal of Cancer Prevention and Treatment, 2022, 29(3):213-216. doi:10.16073/j.cnki.cjcpt.2022.03.10. | |
| [20] | 商在春, 葛彬彬, 李明, 等. 改良型体膜固定板在宫颈癌调强放射治疗中的应用[J]. 生物医学工程与临床, 2023, 27(3):331-336. |
| SHANG Z C, GE B B, LI M, et al. Application of improved membrane fixation plate in cervical cancer intensity-modulated radiotherapy[J]. Biomedical Engineering and Clinical, 2023, 27(3):331-336. doi:10.13339/j.cnki.sglc.20230420.003. | |
| [21] | 赵田地, 姜树坤, 张瑞麟, 等. 基于六自由度床盆腔放疗妇瘤患者不同固定方式的比较分析[J]. 现代肿瘤医学, 2021, 29(23):4192-4195. |
| ZHAO T D, JIANG S K, ZHANG R L, et al. Comparative analysis of different fixation methods for women with pelvic radiotherapy based on six degrees of freedom bed[J]. Modern Oncology Medicine, 2021, 29(23):4192-4195. doi:10.3969/j.issn.1672-4992.2021.23.026. |
| [1] | LIU Xingchen, WANG Fang, SHEN Yong. Expression of Decorin and Mimecan in cervical cancer and their impact on prognostic assessment [J]. Tianjin Medical Journal, 2025, 53(6): 578-583. |
| [2] | WANG Caili, WANG Rui, GUO Lining. The expression level and clinical value of ALKBH5 and PAK5 in high-risk HPV positive cervical cancer tissue [J]. Tianjin Medical Journal, 2025, 53(4): 355-359. |
| [3] | TIAN Youjun, TAN Zhengwu, YANG Ke, PENG Jianmin, CHEN Hongtao, HUANG Zhiping. The predictive value of multi-sequence MRI radiomics in the therapeutic effect of concurrent chemoradiotherapy on locally advanced cervical squamous cell carcinoma [J]. Tianjin Medical Journal, 2025, 53(2): 213-218. |
| [4] | YANG Yan, YANG Wanfu, LI Hailiang, YANG Zhihua. Multivariate analysis of factors influencing prognosis in IDH wild-type glioblastoma [J]. Tianjin Medical Journal, 2025, 53(12): 1290-1294. |
| [5] | HUANG Xiaoqing, LIU Yuanyuan, YAN Liang, YI Shuping. Dosimetric comparison of two irradiation modes after radical mastectomy for breast cancer [J]. Tianjin Medical Journal, 2025, 53(11): 1204-1207. |
| [6] | YANG Yanyan, WANG Ping, YI Xue, PENG Jinzhu, HE Yu, ZHANG Wenyu, CHEN Lei, Aziya . Epidemiological analysis of high-risk HPV infection and genotype distribution in 13 105 women in Zhongguancun area, Beijing [J]. Tianjin Medical Journal, 2025, 53(10): 1086-1090. |
| [7] | LIU Chang, MENG Fanlu, YANG Jing, ZHANG Rongxin, WANG Junping, XIONG Jianhua, ZHONG Diansheng. A case study on multidisciplinary support in comprehensive diagnosis and treatment of combined small cell lung cancer and exploration of MRD [J]. Tianjin Medical Journal, 2025, 53(10): 1091-1097. |
| [8] | HUANG Yuan, WANG Gang, LI Yanling, XIE Ping. Research progress on signaling pathways and drug intervention in radiation-induced heart disease [J]. Tianjin Medical Journal, 2024, 52(8): 888-892. |
| [9] | HUO Jingchen, WANG Yue, LI Hua, QIU Rong, SU Jingwei, WANG Zhuofan, YANG Jie. Predictive value of systemic immune inflammation index (SII) on long-term survival of patients with stage III squamous lung cancer treated with radical radiotherapy [J]. Tianjin Medical Journal, 2024, 52(6): 634-638. |
| [10] | LU Xinyi, DU Weipo, LI Jinggang, GUO Fangfang, ZHANG Xiaolei, LIU Jing. Correlation between serum miR-193a-3p, ATF5 levels and chemotherapy efficacy in patients with triple negative breast cancer [J]. Tianjin Medical Journal, 2024, 52(12): 1313-1316. |
| [11] | YU Ping, ZHOU Min, SU Dan. Construction and validation of chemotherapy resistance prediction model for ovarian cancer [J]. Tianjin Medical Journal, 2024, 52(11): 1177-1182. |
| [12] | WANG Qianqian, LI Tingfang, WANG Feng. Study on the mechanism of CHD4 regulating telomere function to promote cervical cancer HeLa cell proliferation [J]. Tianjin Medical Journal, 2023, 51(9): 909-914. |
| [13] | ZHANG Tianwei, ZHANG Jinbiao, ZHANG Yan, MING Hui, ZHANG Peng, NIE Dong. Changes and clinical significance of serum circPVT1 and miR-486-5p levels before and after radiotherapy for advanced NSCLC [J]. Tianjin Medical Journal, 2023, 51(9): 998-1001. |
| [14] | LONG Ying, HUANG Fangyi, WEI Yousheng. Impacts of NGF/TrkA axis on proliferation, apoptosis and invasion of cervical cancer SiHa cells [J]. Tianjin Medical Journal, 2023, 51(8): 809-813. |
| [15] | WANG Yuning, SONG Juxing, TIAN Zhigang, HAO Guorong, SHEN Hao. The effect of piceatannol on the migration and invasion of cervical cancer cells by regulating miR-106b-5p/RUNX3 axis [J]. Tianjin Medical Journal, 2023, 51(8): 814-819. |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||