Tianjin Medical Journal ›› 2023, Vol. 51 ›› Issue (5): 553-555.doi: 10.11958/20221802

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Research progress on bone marrow mesenchymal stem cells in the treatment of steroid-induced osteonecrosis of femoral head

QIAN Shida(), YU Xuefeng()   

  1. Department of Orthopedics, Fourth Affiliated Hospital of Nanchang University, Nanchang 330003, China
  • Received:2022-11-15 Revised:2023-01-17 Published:2023-05-15 Online:2023-05-05
  • Contact: △E-mail:yxf_1958@sina.com

Abstract:

The etiology and mechanism of steroid-induced osteonecrosis of femoral head (SONFH) have not been fully elucidated, and effective treatments have not yet emerged. With the application of stem cell therapy technology in various disciplines, the nature and function of stem cells have been extensively studied and applied in the treatment of SONFH. However, stem cell transplantation alone is not effective, and its efficacy can be enhanced by pretransplantation modification. This paper reviews the research progress of bone marrow mesenchymal stem cells in the treatment of SONFH.

Key words: femur head necrosis, mesenchymal stem cells, stem cell transplantation, steroid-induced osteonecrosis of the femoral head, bone marrow mesenchymal stem cell

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