Abstract: Objective: To discuss the clinic value of BNP for differential diagnosis in patients with syncope. Method: Eighty-five patients with syncope were divided into cardiac syncope group and non-cardiac syncope group according to many examine. BNP were mensurated for two groups. Result: BNP in cardiac syncope group was 342.8±208.5pg／ml and BNP in non-cardiac syncope group was 52.3±34.4pg／ml. BNP levels had significative statistics difference in two groups. At a cutoff of 150 pg/ml, BNP showed a sensitivity of 87.5%, a specificity of 66.0% and a negative predictive value of 89.7% for the diagnosis of cardiac syncope. Conclusion: BNP levels had important clinic significance for the differential diagnosis of cardiac syncope and non-cardiac syncope.

Key words: Natriuretic peptide, Syncope, Cardiac, Differential diagnosis