Tianjin Med J ›› 2015, Vol. 43 ›› Issue (12): 1447-1449.doi: 10.11958/j.issn.0253-9896.2015.12.027

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Effect of various anaesthesia depth on the sublingual microcirculation

LIU Zhihui1, 2, WANG Guolin1, LI Peibo2, XIE Keliang1, LIU Lingling1, YU Yonghao1△   

  1. 1 Department of Anesthesiology, Tianjin Medical University General Hospital, Tianjin 300052, China; 2 Department of Anesthesiology, Baotou Central Hospital
  • Received:2015-03-09 Revised:2015-07-15 Published:2015-12-15 Online:2015-12-11
  • Contact: △Corresponding Author E-mail:yuyonghao@126.com E-mail:yuyonghao@126.com

Abstract: Objective To investigate the effects of different depth of anesthesia on sublingual microcirculation. Meth⁃ ods ASA grade Ⅰ-Ⅱ patients (n=20) were scheduled for elective thyroid surgery and included in the prospective observa⁃ tional study. Midazolam 0.05 mg·kg, sufentanil 0.3 μg·kg-1 and rocuronium 0.6 mg·kg-1 were administrated intravenously to induce anesthesia which was then maintained by continuous intravenous infusion of propofol. Target medication concentra⁃ tion increased 0.5 mg·L-1, regulated based on BIS. The patients underwent endotracheal intubation and mechanical ventila⁃ tion. Sublingual microcirculations were evaluated by sidestream dark field (SDF) imaging at T1 (BIS baseline ), T2 (50 < BIS ≤ 60), T3 (40 0.05). Conclusion When BIS value sit between 40 and 50, it can best inhibit stress response and attenuate the agitation of microcirculation.

Key words: microcirculation, tongue, stress, depth of anesthesia, bispectral index (BIS), sidestream dark-field technique