Abstract: Abstract: Objective To observe the hemostatic efficacy and safety of argon plasma coagulation (APC) through bron⁃ choscope after biopsy. Methods The APC was given to patients suffered from coronary heart disease combined hyperten⁃ sion or paroxysmal auricular fibrillation and accepted bronchoscopy biopsy with much bleeding. The hemostatic effect and changes of heart rate, blood pressure and SPO2 were observed before and after treatment. Results Sixty-two patients were treated with endoscopic hemostasis by APC. The hemostasis was successful in 60 cases. The hemostasis was performed with APC successfully in 2 patients after intubation and mechanical ventilation because of the biopsy hemorrhage. Sixty-two cas⁃ es included 42 cases of airway tumor (26 cases in lobe bronchus and 16 in segmental bronchus), 16 cases of broadening of the trachea ridge and mucosal rough, and 4 cases of granulation tissue of lobe bronchus. There were no significant differenc⁃ es in mean arterial pressure and heart rate before and after treatment in 60 patients (P > 0.05). The oxygen saturation was sig⁃ nificantly lower after treatment than that before treatment (0.939±0.027 vs. 0.956±0.017, P < 0.05). Conclusion Hemosta⁃ sis treatment by APC through bronchoscope has the characteristics of rapid, thorough and safe, especially for patients com⁃ bined with cardiovascular disease. It can avoid the occurrence of cardiovascular system complications caused by convention⁃ al hemostatic treatment.

Key words: bronchoscopy, biopsy, hemorrhage, hemostasis, argon plasma coagulation