Tianjin Medical Journal ›› 2023, Vol. 51 ›› Issue (3): 290-293.doi: 10.11958/20221230
• Clinical Research • Previous Articles Next Articles
LIU Zhichao1(), XU Ke△(
), BU Haixia2, DOU Xianfeng1
Received:
2022-08-09
Revised:
2022-09-13
Published:
2023-03-15
Online:
2023-03-02
Contact:
XU Ke
E-mail:451811089@qq.com;xukemingze@163.com
LIU Zhichao, XU Ke, BU Haixia, DOU Xianfeng. Predictive value of prognostic nutritional index combined with NLR and PLR in all-cause mortality of patients with peritoneal dialysis[J]. Tianjin Medical Journal, 2023, 51(3): 290-293.
CLC Number:
组别 | n | 年龄 (岁) | 性别 (男/女) | 腹透时间 (月) | 高血压 | 糖尿病 | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
存活组 | 118 | 48.34±13.69 | 65/53 | 60.67±25.55 | 75(63.6) | 19(16.1) | ||||||||||||||||||||
死亡组 | 71 | 59.44±12.43 | 47/24 | 34.51±21.34 | 68(95.8) | 23(32.4) | ||||||||||||||||||||
t、χ2或Z | 5.587** | 2.267 | 7.240** | 24.982** | 6.808** | |||||||||||||||||||||
组别 | TG (mmol/L) | TC (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | UA (μmol/L) | |||||||||||||||||||||
存活组 | 1.47±0.70 | 4.82±1.35 | 1.20±0.31 | 2.82±1.02 | 431.47±139.78 | |||||||||||||||||||||
死亡组 | 1.60±0.75 | 5.00±1.43 | 1.22±0.25 | 3.07±1.01 | 459.15±166.84 | |||||||||||||||||||||
t、χ2或Z | 1.222 | 0.844 | 0.380 | 1.632 | 1.225 | |||||||||||||||||||||
组别 | K+(mmol/L) | Na+(mmol/L) | Cl-(mmol/L) | Ca2+(mmol/L) | ||||||||||||||||||||||
存活组 | 4.50±0.89 | 140.92±3.40 | 101.88±10.47 | 1.95(1.77,2.09) | ||||||||||||||||||||||
死亡组 | 4.82±0.96 | 140.15±3.22 | 102.48±9.23 | 2.00(1.82,2.13) | ||||||||||||||||||||||
t、χ2或Z | 2.351 | 1.536 | 0.399 | 1.412 | ||||||||||||||||||||||
组别 | Mg2+ (mmol/L) | P3+ (mmol/L) | TP (g/L) | ALB (g/L) | GLU (mmol/L) | |||||||||||||||||||||
存活组 | 0.95±0.20 | 1.80±0.52 | 57.68±7.80 | 33.56±5.83 | 5.57±3.70 | |||||||||||||||||||||
死亡组 | 0.94±0.21 | 1.69±0.52 | 57.41±9.73 | 32.64±4.90 | 5.91±3.11 | |||||||||||||||||||||
t、χ2或Z | 0.203 | 1.378 | 0.208 | 1.099 | 0.632 | |||||||||||||||||||||
组别 | HGB(g/L) | NLR | PLR | PNI | ||||||||||||||||||||||
存活组 | 83.03±17.46 | 3.73±2.24 | 137.61±34.68 | 54.63±13.40 | ||||||||||||||||||||||
死亡组 | 79.21±19.50 | 4.97±2.22 | 168.26±52.58 | 43.28±12.91 | ||||||||||||||||||||||
t、χ2或Z | 1.395 | 3.711** | 4.826** | 5.713** |
Tab.1 Comparison of general data between the death group and the survival group
组别 | n | 年龄 (岁) | 性别 (男/女) | 腹透时间 (月) | 高血压 | 糖尿病 | ||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
存活组 | 118 | 48.34±13.69 | 65/53 | 60.67±25.55 | 75(63.6) | 19(16.1) | ||||||||||||||||||||
死亡组 | 71 | 59.44±12.43 | 47/24 | 34.51±21.34 | 68(95.8) | 23(32.4) | ||||||||||||||||||||
t、χ2或Z | 5.587** | 2.267 | 7.240** | 24.982** | 6.808** | |||||||||||||||||||||
组别 | TG (mmol/L) | TC (mmol/L) | HDL-C (mmol/L) | LDL-C (mmol/L) | UA (μmol/L) | |||||||||||||||||||||
存活组 | 1.47±0.70 | 4.82±1.35 | 1.20±0.31 | 2.82±1.02 | 431.47±139.78 | |||||||||||||||||||||
死亡组 | 1.60±0.75 | 5.00±1.43 | 1.22±0.25 | 3.07±1.01 | 459.15±166.84 | |||||||||||||||||||||
t、χ2或Z | 1.222 | 0.844 | 0.380 | 1.632 | 1.225 | |||||||||||||||||||||
组别 | K+(mmol/L) | Na+(mmol/L) | Cl-(mmol/L) | Ca2+(mmol/L) | ||||||||||||||||||||||
存活组 | 4.50±0.89 | 140.92±3.40 | 101.88±10.47 | 1.95(1.77,2.09) | ||||||||||||||||||||||
死亡组 | 4.82±0.96 | 140.15±3.22 | 102.48±9.23 | 2.00(1.82,2.13) | ||||||||||||||||||||||
t、χ2或Z | 2.351 | 1.536 | 0.399 | 1.412 | ||||||||||||||||||||||
组别 | Mg2+ (mmol/L) | P3+ (mmol/L) | TP (g/L) | ALB (g/L) | GLU (mmol/L) | |||||||||||||||||||||
存活组 | 0.95±0.20 | 1.80±0.52 | 57.68±7.80 | 33.56±5.83 | 5.57±3.70 | |||||||||||||||||||||
死亡组 | 0.94±0.21 | 1.69±0.52 | 57.41±9.73 | 32.64±4.90 | 5.91±3.11 | |||||||||||||||||||||
t、χ2或Z | 0.203 | 1.378 | 0.208 | 1.099 | 0.632 | |||||||||||||||||||||
组别 | HGB(g/L) | NLR | PLR | PNI | ||||||||||||||||||||||
存活组 | 83.03±17.46 | 3.73±2.24 | 137.61±34.68 | 54.63±13.40 | ||||||||||||||||||||||
死亡组 | 79.21±19.50 | 4.97±2.22 | 168.26±52.58 | 43.28±12.91 | ||||||||||||||||||||||
t、χ2或Z | 1.395 | 3.711** | 4.826** | 5.713** |
指标 | AUC(95%CI) | 敏感度 (%) | 特异度 (%) | 约登 指数 | 最佳 临界值 | Z |
---|---|---|---|---|---|---|
NLR | 0.684(0.612~0.749) | 57.75 | 79.66 | 0.374 | 4.91 | 4.553** |
PLR | 0.689(0.618~0.754) | 67.61 | 68.64 | 0.362 | 152.92 | 4.481** |
PNI | 0.729(0.660~0.791) | 57.75 | 80.51 | 0.383 | 43.74 | 6.047** |
联合指标 | 0.842(0.782~0.891) | 87.32 | 68.64 | 0.560 | - | 12.330** |
Tab.2 Clinical values of NLR, PLR, PNI and their combination in predicting death in patients with PD
指标 | AUC(95%CI) | 敏感度 (%) | 特异度 (%) | 约登 指数 | 最佳 临界值 | Z |
---|---|---|---|---|---|---|
NLR | 0.684(0.612~0.749) | 57.75 | 79.66 | 0.374 | 4.91 | 4.553** |
PLR | 0.689(0.618~0.754) | 67.61 | 68.64 | 0.362 | 152.92 | 4.481** |
PNI | 0.729(0.660~0.791) | 57.75 | 80.51 | 0.383 | 43.74 | 6.047** |
联合指标 | 0.842(0.782~0.891) | 87.32 | 68.64 | 0.560 | - | 12.330** |
指标 | β | SE | Wald χ2 | P | HR | HR 95%CI |
---|---|---|---|---|---|---|
年龄 | 0.027 | 0.009 | 8.631 | 0.003 | 1.028 | 1.009~1.047 |
高血压 | 0.878 | 0.265 | 10.952 | 0.001 | 2.406 | 1.430~4.046 |
糖尿病 | 0.611 | 0.270 | 5.110 | 0.024 | 1.843 | 1.085~3.131 |
PNI | 1.030 | 0.255 | 16.371 | <0.001 | 2.802 | 1.701~4.616 |
PLR | 1.046 | 0.271 | 14.847 | <0.001 | 2.846 | 1.672~4.844 |
NLR | 0.820 | 0.256 | 10.252 | 0.001 | 2.271 | 1.375~3.753 |
Tab.3 Multivariate Cox regression risk analysis of all-cause mortality in PD patients
指标 | β | SE | Wald χ2 | P | HR | HR 95%CI |
---|---|---|---|---|---|---|
年龄 | 0.027 | 0.009 | 8.631 | 0.003 | 1.028 | 1.009~1.047 |
高血压 | 0.878 | 0.265 | 10.952 | 0.001 | 2.406 | 1.430~4.046 |
糖尿病 | 0.611 | 0.270 | 5.110 | 0.024 | 1.843 | 1.085~3.131 |
PNI | 1.030 | 0.255 | 16.371 | <0.001 | 2.802 | 1.701~4.616 |
PLR | 1.046 | 0.271 | 14.847 | <0.001 | 2.846 | 1.672~4.844 |
NLR | 0.820 | 0.256 | 10.252 | 0.001 | 2.271 | 1.375~3.753 |
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