Research progress of CREB in angiogenesis, anti-apoptosis and lung cancer

doi:10.11958/20182109

Tianjin Med J ›› 2019, Vol. 47 ›› Issue (4): 431-435.doi: 10.11958/20182109

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Research progress of CREB in angiogenesis, anti-apoptosis and lung cancer

LIU Xiao, DUAN Yong, ZHANG Yan-liang

Yunnan Key Laboratory of Laboratory Medicine, Department of Clinical Laboratory, the First Affiliated Hospital of Kunming Medical University, Yunnan Institute of Experimental Diagnosis, Kunming 650032, China

Received:2018-12-21 Revised:2019-01-15 Published:2019-04-15 Online:2019-05-27
Contact: Xiao Liu E-mail:18088446698@163.com
Supported by:
Expression and Mechanism of CREB3L4 Gene in Xuanwei Lung Cancer in Yunnan Province;The role and molecular mechanism of CREB3L4 in the pathogenesis of lung cancer in Xuanwei, Yunnan

LIU Xiao, DUAN Yong, ZHANG Yan-liang. Research progress of CREB in angiogenesis, anti-apoptosis and lung cancer[J]. Tianjin Med J, 2019, 47(4): 431-435.

Abstract

Abstract: cAMP-response element binding protein (CREB) has been widely studied as a transcriptional factor in the field of long-term memory formation and the development and treatment of various malignant tumors. This review summarized the research progress of CREB gene in neovascularization, cell proliferation and anti-apoptosis, and the relationship between CREB geen and the carcinogenic process of nicotine and tumors (especially lung cancer) in order to provide references for future research of CREB family proteins.

Key words: cyclic AMP response element-binding protein, neovascularization, pathologic, apoptosis, nicotine, lung neoplasms, carcinoma

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Research progress of CREB in angiogenesis, anti-apoptosis and lung cancer

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