Abstract: Objective To evaluate the predictive values of SYNTAX score (SS) and SYNTAX score Ⅱ (SS-Ⅱ) for the long-term outcomes of patients after coronary artery bypass grafting (CABG). Methods Data of 308 consecutive patients underwent CABG were collected in this study. The SS and SS-Ⅱ scores were calculated for each patient. Patients were stratified into low, middle and high score groups according to the tertiles of SS and SS-Ⅱ. The major adverse cardiovascular events (MACE) were followed up for patients. Kaplan-Meier was used for survival analysis. ROC curve and Cox regression analysis were used to evaluate the predictive values of SS and SS-Ⅱ for MACE. Results At a median follow-up of 63 months, the cumulative incidence of MACE was 30.5%. According to either SS or SS-Ⅱ, there were significant differences in MACE, repeat revascularization and non-fatal myocardial infarction between the three groups (P＜0.01). There were significant differences in the cumulative survival rates of non-MACE between three groups (P＜0.01). SS (AUC=0.664) and SS-Ⅱ (AUC=0.751) were reliable predictors of MACE. The predictive effect of SS-Ⅱ for MACE was significantly higher than that of SS (Z=2.296，P＜0.05). Multivariate Cox regression analysis showed that SS (HR 2.577 for the middle group; HR 4.428 for the high group) and SS-Ⅱ (HR 2.343 for the middle group; HR 5.108 for the high group) were risk factors for MACE. Conclusion Both SS and SS-Ⅱ are correlated with MACE in patients after CABG, and they are predictors for evaluating the long-term prognosis of patients with coronary heart disease treated with CABG. The predictive value of SS-Ⅱ for MACE is better than that of SS.

Key words: coronary disease, prognosis, coronary artery bypass, SYNTAX score, SYNTAX score Ⅱ, major adverse cardiovascular events