Research progress of long non-coding RNA regulating metastasis of gastric cancer

doi:10.11958/20221140

Abstract

Abstract:

Gastric cancer is a common cancer of the digestive system with a high mortality rate. Distant metastasis of tumor cells is one of main causes of treatment failure and patient death. Finding therapeutic targets for gastric cancer metastasis is of great significance for improving the survival rate of patients. A large number of recent studies have shown that long non-coding RNAs (LncRNAs) are closely related to the metastasis of gastric cancer, and they are involved in various biological processes of gastric cancer metastasis. Therefore, this article reviews the research progress in the regulation of gastric cancer metastasis by LncRNA, in order to provide a theoretical basis for understanding the mechanism of gastric cancer metastasis.

Key words: stomach neoplasms, RNA, long noncoding, neoplasm metastasis, tumor escape, neovascularization, pathologic, epithelial-mesenchymal transition

CLC Number:

R737.9

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