Research progress in the pathogenesis of sepsis-related intestinal dysfunction

doi:10.11958/20221492

Abstract

Abstract:

Sepsis-related intestinal dysfunction is a common but neglected complication in patients with sepsis. Its pathogenesis is not fully understood. At present, possible mechanisms include intestinal microecological imbalance, abnormal intestinal cell death and mitochondrial dysfunction. Because the pathogenesis of this complication is unclear, and existing therapeutic means offer limited improvement in patient prognosis, this article reviews the current research status of the pathogenesis of sepsis related intestinal dysfunction in order to find new clinical treatment options for sepsis related intestinal dysfunction.

Key words: sepsis, intestinal diseases, apoptosis, ferroptosis, pyroptosis, mitophagy, intestinal microecology

CLC Number:

R574.4

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