Abstract:

[Abstract]   Objective   To evaluate the subjective and objective improvement of quality of life in patients with lowtemperature plasma- assisted modified uvulopalatopharyngoplasty (H- UPPP) combined with lymphoidectomy in radix lin?guae and coblation-channeling of the tongue(CCT) treating for severe obstructive sleep apnea hypopnea syndrome (OSAHS)，and compare the surgical efficacy with that of H-UPPP.  Methods   A total of81patients with severe OSAHS were divided into treatment group (n=42) and control group (n=39). Treatment group underwent the low-temperature plasma-assisted HUPPP combining lymphoidectomy in radix linguae and CCT，and control group underwent H-UPPP treatment. The apnea hypopnea index (AHI), the lowest saturation of arterial oxygen (LSaO2) and Quebec sleep questionnaire (QSQ) and Epworthsleepiness scale (ESS) before operation and6-month after operation were recorded and compared between two groups.  Results   All of detection indicators were significantly improved after operation in treatment group (P<0.01). The total surgicalefficacy was significantly higher in treatment group than that of control group (83.3%vs12.8%，χ2=40.225，P＜0.01). The total improvement rate of five dimensions in QSQ such as daytime sleepiness symptoms (76.2%vs25.6%), signs during the day(71.4%vs10.2%) and night (54.8%vs5.1%), emotion (54.8%vs2.5%), ability of social intercourse (50.0%vs2.5%) and thetotal score (57.1%vs7.7%) after operation were significantly higher in treatment group than those of control group. The severe indexes of ESS decreased to23.8% after operation in treatment group than those of control group (51.3%).   Conclusion    Low-temperature plasma-assisted H-UPPP combined with lymphoidectomy in radix linguae and CCT is effective in patients with severe OSAHS, which can also improve the quality of life postoperatively.

Key words: sleep apnea, obstructive, uvula, catheter ablation, electromyography, polysomnography, quality of life, 外科手术