Abstract: Abstract: Rotator cuff injury is a common shoulder disease, which often results in pain and limited motion of shoulder and reduces the quality of life. There are some limitations for current treatments, which often lead to repair failure or reinjury of rotator cuff. Therefore, a novel repair technique is needed. Biologic repair represents a novel technique in the management of rotator cuff injury, and has the potential to restore the normal histological structure of rotator cuff. Biologic repair involves the application of growth factors and/ or cells to promote the regeneration of rotator cuff tendons. This study reviewed the literatures on biologic repair of rotator cuff injury, and presented the research progress.

Key words: Key words: stem cells, growth factor, rotator cuff injury, biologic repair, review