Abstract: Objective We summarized the different types and characteristics of pulmonary function changes in children with mycoplasma pneumoniae pneumonia (MPP), and look for risk factors for changes in lung function. Methods A total of 230 children with MPP hospitalized between July 2017 and December 2018 were selected in this study. The children were divided into abnormal group (n=50, there were 38 cases of ventilation disorders and 12 cases of diffusion disorders) and normal group (n=180) according to whether pulmonary function changes occurred. The types and characteristics of pulmonary function changes in abnormal group were analyzed, and the differences of basic conditions,clinical manifestations, changes of pulmonary function and related auxiliary examinations were compared between the two groups. Results There were significantly longer values in hospitalization time, fever time, proportion of hypopnea, Creactive protein (CRP) and lactatedehydrogenase (LDH) in abnormal group than that of normal group (P＜0.05). The Logistic regression analysis showed that extended heating time (OR=2.276, 95%CI: 1.658-3.125), extended hospitalization time (OR=1.976, 95%CI: 1.478-2.642), and CRP elevation (OR=1.112, 95%CI: 1.056-1.170) were the risk factors of pulmonary function changes in MPP (P＜0.05).Conclusion The main pulmonary function changes in MPP children are ventilation disorders, but there are also some diffusion disorders. Long-term fever, prolonged course of disease and increased CRP in acute stage are the high risk factors leading to pulmonary function changes in MPP children.

Key words: pneumonia, mycoplasma, child, hypoventilation, risk factors, pulmonary function