Tianjin Medical Journal ›› 2022, Vol. 50 ›› Issue (9): 1002-1008.doi: 10.11958/20212862

• Review • Previous Articles    

Research progress in anti-inflammatory activity of insect antimicrobial peptides and anti-inflammatory mechanism based on signal pathway

CUI Huicheng(), XIA Qiang()   

  1. Zhuhai Campus of Zunyi Medical University/ Education and Innovation Base for Immunology Graduate Students in Guizhou Province, Zhuhai 519041, China
  • Received:2021-12-31 Revised:2022-04-28 Published:2022-09-15 Online:2022-09-05
  • Contact: XIA Qiang E-mail:782198846@qq.com;xiaqiang1973@126.com

Abstract:

Insect antimicrobial peptides are the general name of immune active substances produced by insects to resist the infection of external pathogenic microorganisms. Their excellent anti-inflammatory activity makes them have broad application prospects. In this paper, the anti-inflammatory activities and their possible signaling pathways of different insect antimicrobial peptides were reviewed, and the current status of clinical research on insect antimicrobial peptides was introduced, in order to provide references for the application of insect antimicrobial peptides.

Key words: anti-inflammatory drugs (TCD), antimicrobial peptide, insect, signaling pathway, anti-inflammatory activity

CLC Number: